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Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Singaraja RR, Van Eck M, Bissada N, Zimetti F, Collins HL, Hildebrand RB, Hayden A, Brunham LR, Kang MH, Fruchart JC, Van Berkel TJ, Parks JS, Staels B, Rothblat GH, Fiévet C, Hayden MR. Singaraja RR, et al. Circulation. 2006 Sep 19;114(12):1301-9. doi: 10.1161/CIRCULATIONAHA.106.621433. Epub 2006 Aug 28. Circulation. 2006. PMID: 16940190
ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.
Trigueros-Motos L, van Capelleveen JC, Torta F, Castaño D, Zhang LH, Chai EC, Kang M, Dimova LG, Schimmel AWM, Tietjen I, Radomski C, Tan LJ, Thiam CH, Narayanaswamy P, Wu DH, Dorninger F, Yakala GK, Barhdadi A, Angeli V, Dubé MP, Berger J, Dallinga-Thie GM, Tietge UJF, Wenk MR, Hayden MR, Hovingh GK, Singaraja RR. Trigueros-Motos L, et al. Among authors: singaraja rr. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2147-2155. doi: 10.1161/ATVBAHA.117.309574. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882873
Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Brunham LR, Singaraja RR, Duong M, Timmins JM, Fievet C, Bissada N, Kang MH, Samra A, Fruchart JC, McManus B, Staels B, Parks JS, Hayden MR. Brunham LR, et al. Among authors: singaraja rr. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):548-54. doi: 10.1161/ATVBAHA.108.182303. Epub 2009 Feb 5. Arterioscler Thromb Vasc Biol. 2009. PMID: 19201688
89 results