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Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio.
Jiang Z, Vasil AI, Gera L, Vasil ML, Hodges RS. Jiang Z, et al. Among authors: hodges rs. Chem Biol Drug Des. 2011 Apr;77(4):225-40. doi: 10.1111/j.1747-0285.2011.01086.x. Epub 2011 Feb 2. Chem Biol Drug Des. 2011. PMID: 21219588 Free PMC article.
381 results