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Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation.
Viswanathan J, Haapasalo A, Böttcher C, Miettinen R, Kurkinen KM, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Bertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M. Viswanathan J, et al. Among authors: romano d. Traffic. 2011 Mar;12(3):330-48. doi: 10.1111/j.1600-0854.2010.01149.x. Epub 2011 Jan 7. Traffic. 2011. PMID: 21143716 Free PMC article.
Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion.
Hiltunen M, Lu A, Thomas AV, Romano DM, Kim M, Jones PB, Xie Z, Kounnas MZ, Wagner SL, Berezovska O, Hyman BT, Tesco G, Bertram L, Tanzi RE. Hiltunen M, et al. J Biol Chem. 2006 Oct 27;281(43):32240-53. doi: 10.1074/jbc.M603106200. Epub 2006 Aug 31. J Biol Chem. 2006. PMID: 16945923 Free article.
Effects of ubiquilin 1 on the unfolded protein response.
Lu A, Hiltunen M, Romano DM, Soininen H, Hyman BT, Bertram L, Tanzi RE. Lu A, et al. J Mol Neurosci. 2009 May;38(1):19-30. doi: 10.1007/s12031-008-9155-6. Epub 2008 Oct 25. J Mol Neurosci. 2009. PMID: 18953672
600 results