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The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.
Völkers M, Weidenhammer C, Herzog N, Qiu G, Spaich K, Wegner FV, Peppel K, Müller OJ, Schinkel S, Rabinowitz JE, Hippe HJ, Brinks H, Katus HA, Koch WJ, Eckhart AD, Friedrich O, Most P. Völkers M, et al. Among authors: peppel k. Circ Res. 2011 Jan 7;108(1):27-39. doi: 10.1161/CIRCRESAHA.110.225201. Epub 2010 Nov 24. Circ Res. 2011. PMID: 21106943 Free PMC article.
S100A1 deficiency impairs postischemic angiogenesis via compromised proangiogenic endothelial cell function and nitric oxide synthase regulation.
Most P, Lerchenmüller C, Rengo G, Mahlmann A, Ritterhoff J, Rohde D, Goodman C, Busch CJ, Laube F, Heissenberg J, Pleger ST, Weiss N, Katus HA, Koch WJ, Peppel K. Most P, et al. Among authors: peppel k. Circ Res. 2013 Jan 4;112(1):66-78. doi: 10.1161/CIRCRESAHA.112.275156. Epub 2012 Oct 9. Circ Res. 2013. PMID: 23048072 Free PMC article.
S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4.
Rohde D, Schön C, Boerries M, Didrihsone I, Ritterhoff J, Kubatzky KF, Völkers M, Herzog N, Mähler M, Tsoporis JN, Parker TG, Linke B, Giannitsis E, Gao E, Peppel K, Katus HA, Most P. Rohde D, et al. Among authors: peppel k. EMBO Mol Med. 2014 Jun;6(6):778-94. doi: 10.15252/emmm.201303498. Epub 2014 Apr 6. EMBO Mol Med. 2014. PMID: 24833748 Free PMC article.
S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling.
Lerchenmüller C, Heißenberg J, Damilano F, Bezzeridis VJ, Krämer I, Bochaton-Piallat ML, Hirschberg K, Busch M, Katus HA, Peppel K, Rosenzweig A, Busch H, Boerries M, Most P. Lerchenmüller C, et al. Among authors: peppel k. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1854-67. doi: 10.1161/ATVBAHA.115.306415. Epub 2016 Jul 7. Arterioscler Thromb Vasc Biol. 2016. PMID: 27386938 Free PMC article.
Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density.
Li X, Mikhalkova D, Gao E, Zhang J, Myers V, Zincarelli C, Lei Y, Song J, Koch WJ, Peppel K, Cheung JY, Feldman AM, Chan TO. Li X, et al. Among authors: peppel k. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1932-40. doi: 10.1152/ajpheart.00755.2010. Epub 2011 Sep 2. Am J Physiol Heart Circ Physiol. 2011. PMID: 21890689 Free PMC article.
52 results