Motshwene PG - Search Results

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Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.

George J, Motshwene PG, Wang H, Kubarenko AV, Rautanen A, Mills TC, Hill AV, Gay NJ, Weber AN. George J, et al. Among authors: motshwene pg. J Biol Chem. 2011 Jan 14;286(2):1341-53. doi: 10.1074/jbc.M110.159996. Epub 2010 Oct 21. J Biol Chem. 2011. PMID: 20966070 Free PMC article.

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.

Dossang AC, Motshwene PG, Yang Y, Symmons MF, Bryant CE, Borman S, George J, Weber AN, Gay NJ. Dossang AC, et al. Among authors: motshwene pg. Sci Rep. 2016 Nov 23;6:37267. doi: 10.1038/srep37267. Sci Rep. 2016. PMID: 27876844 Free PMC article.

An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.

Motshwene PG, Moncrieffe MC, Grossmann JG, Kao C, Ayaluru M, Sandercock AM, Robinson CV, Latz E, Gay NJ. Motshwene PG, et al. J Biol Chem. 2009 Sep 11;284(37):25404-11. doi: 10.1074/jbc.M109.022392. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592493 Free PMC article.

Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells.

El Maadidi S, Weber ANR, Motshwene P, Schüssler JM, Backes D, Dickhöfer S, Wang H, Liu X, Garcia MD, Taumer C, Soufi B, Wolz OO, Klimosch SN, Franz-Wachtel M, Macek B, Gay NJ. El Maadidi S, et al. Sci Rep. 2019 Sep 11;9(1):13168. doi: 10.1038/s41598-019-49017-z. Sci Rep. 2019. PMID: 31511529 Free PMC article.

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