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Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Lara E, Mai A, Calvanese V, Altucci L, Lopez-Nieva P, Martinez-Chantar ML, Varela-Rey M, Rotili D, Nebbioso A, Ropero S, Montoya G, Oyarzabal J, Velasco S, Serrano M, Witt M, Villar-Garea A, Imhof A, Mato JM, Esteller M, Fraga MF. Lara E, et al. Among authors: montoya g. Oncogene. 2009 Feb 12;28(6):781-91. doi: 10.1038/onc.2008.436. Epub 2008 Dec 8. Oncogene. 2009. PMID: 19060927
SUMOylation modulates the function of Aurora-B kinase.
Fernández-Miranda G, Pérez de Castro I, Carmena M, Aguirre-Portolés C, Ruchaud S, Fant X, Montoya G, Earnshaw WC, Malumbres M. Fernández-Miranda G, et al. Among authors: montoya g. J Cell Sci. 2010 Aug 15;123(Pt 16):2823-33. doi: 10.1242/jcs.065565. Epub 2010 Jul 27. J Cell Sci. 2010. PMID: 20663916 Free PMC article.
Non-specific protein-DNA interactions control I-CreI target binding and cleavage.
Molina R, Redondo P, Stella S, Marenchino M, D'Abramo M, Gervasio FL, Epinat JC, Valton J, Grizot S, Duchateau P, Prieto J, Montoya G. Molina R, et al. Among authors: montoya g. Nucleic Acids Res. 2012 Aug;40(14):6936-45. doi: 10.1093/nar/gks320. Epub 2012 Apr 11. Nucleic Acids Res. 2012. PMID: 22495931 Free PMC article.
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, Duchateau P, Alibés A, Stricher F, Serrano L, Blanco FJ, Montoya G. Muñoz IG, et al. Among authors: montoya g. Nucleic Acids Res. 2011 Jan;39(2):729-43. doi: 10.1093/nar/gkq801. Epub 2010 Sep 16. Nucleic Acids Res. 2011. PMID: 20846960 Free PMC article.
Comprehensive analysis of the specificity of transcription activator-like effector nucleases.
Juillerat A, Dubois G, Valton J, Thomas S, Stella S, Maréchal A, Langevin S, Benomari N, Bertonati C, Silva GH, Daboussi F, Epinat JC, Montoya G, Duclert A, Duchateau P. Juillerat A, et al. Among authors: montoya g. Nucleic Acids Res. 2014 Apr;42(8):5390-402. doi: 10.1093/nar/gku155. Epub 2014 Feb 24. Nucleic Acids Res. 2014. PMID: 24569350 Free PMC article.
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors.
Pastor J, Oyarzabal J, Saluste G, Alvarez RM, Rivero V, Ramos F, Cendón E, Blanco-Aparicio C, Ajenjo N, Cebriá A, Albarrán MI, Cebrián D, Corrionero A, Fominaya J, Montoya G, Mazzorana M. Pastor J, et al. Among authors: montoya g. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1591-7. doi: 10.1016/j.bmcl.2011.12.130. Epub 2012 Jan 5. Bioorg Med Chem Lett. 2012. PMID: 22266039
247 results