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Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.
Lu ZH, Shvartsman MB, Lee AY, Shao JM, Murray MM, Kladney RD, Fan D, Krajewski S, Chiang GG, Mills GB, Arbeit JM. Lu ZH, et al. Among authors: arbeit jm. Cancer Res. 2010 Apr 15;70(8):3287-98. doi: 10.1158/0008-5472.CAN-09-3467. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388784 Free PMC article.
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