Kahn CR - Search Results

1

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

Welsh GI, Hale LJ, Eremina V, Jeansson M, Maezawa Y, Lennon R, Pons DA, Owen RJ, Satchell SC, Miles MJ, Caunt CJ, McArdle CA, Pavenstädt H, Tavaré JM, Herzenberg AM, Kahn CR, Mathieson PW, Quaggin SE, Saleem MA, Coward RJM. Welsh GI, et al. Among authors: kahn cr. Cell Metab. 2010 Oct 6;12(4):329-340. doi: 10.1016/j.cmet.2010.08.015. Cell Metab. 2010. PMID: 20889126 Free PMC article.

2

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity.

White MF, Livingston JN, Backer JM, Lauris V, Dull TJ, Ullrich A, Kahn CR. White MF, et al. Among authors: kahn cr. Cell. 1988 Aug 26;54(5):641-9. doi: 10.1016/s0092-8674(88)80008-4. Cell. 1988. PMID: 2842060

3

Insulin action and the insulin signaling network.

Cheatham B, Kahn CR. Cheatham B, et al. Among authors: kahn cr. Endocr Rev. 1995 Apr;16(2):117-42. doi: 10.1210/edrv-16-2-117. Endocr Rev. 1995. PMID: 7781591 Review. No abstract available.

4

The insulin signaling system.

White MF, Kahn CR. White MF, et al. Among authors: kahn cr. J Biol Chem. 1994 Jan 7;269(1):1-4. J Biol Chem. 1994. PMID: 8276779 Free article. Review. No abstract available.

5

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles.

Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Cell. 1997 Feb 21;88(4):561-72. doi: 10.1016/s0092-8674(00)81896-6. Cell. 1997. PMID: 9038347 Free article.

6

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.

Brüning JC, Michael MD, Winnay JN, Hayashi T, Hörsch D, Accili D, Goodyear LJ, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell. 1998 Nov;2(5):559-69. doi: 10.1016/s1097-2765(00)80155-0. Mol Cell. 1998. PMID: 9844629 Free article.

7

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

8

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance.

Virkamäki A, Ueki K, Kahn CR. Virkamäki A, et al. Among authors: kahn cr. J Clin Invest. 1999 Apr;103(7):931-43. doi: 10.1172/JCI6609. J Clin Invest. 1999. PMID: 10194465 Free PMC article. Review. No abstract available.

9

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.

Wojtaszewski JF, Higaki Y, Hirshman MF, Michael MD, Dufresne SD, Kahn CR, Goodyear LJ. Wojtaszewski JF, et al. Among authors: kahn cr. J Clin Invest. 1999 Nov;104(9):1257-64. doi: 10.1172/JCI7961. J Clin Invest. 1999. PMID: 10545524 Free PMC article.

10

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction.

Michael MD, Kulkarni RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn CR. Michael MD, et al. Among authors: kahn cr. Mol Cell. 2000 Jul;6(1):87-97. Mol Cell. 2000. PMID: 10949030 Free article.

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