Lehrach H - Search Results

1

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage.

Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmermann B, Lehrach H, Herwig R, Adjaye J. Chavez L, et al. Among authors: lehrach h. Genome Res. 2010 Oct;20(10):1441-50. doi: 10.1101/gr.110114.110. Epub 2010 Aug 27. Genome Res. 2010. PMID: 20802089 Free PMC article.

2

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach.

Chavez L, Bais AS, Vingron M, Lehrach H, Adjaye J, Herwig R. Chavez L, et al. Among authors: lehrach h. BMC Genomics. 2009 Jul 15;10:314. doi: 10.1186/1471-2164-10-314. BMC Genomics. 2009. PMID: 19604364 Free PMC article.

3

Molecular characterization of cultured adult human liver progenitor cells.

Jozefczuk J, Stachelscheid H, Chavez L, Herwig R, Lehrach H, Zeilinger K, Gerlach JC, Adjaye J. Jozefczuk J, et al. Among authors: lehrach h. Tissue Eng Part C Methods. 2010 Oct;16(5):821-34. doi: 10.1089/ten.TEC.2009.0578. Tissue Eng Part C Methods. 2010. PMID: 19874131

4

Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming.

Prigione A, Lichtner B, Kuhl H, Struys EA, Wamelink M, Lehrach H, Ralser M, Timmermann B, Adjaye J. Prigione A, et al. Among authors: lehrach h. Stem Cells. 2011 Sep;29(9):1338-48. doi: 10.1002/stem.683. Stem Cells. 2011. PMID: 21732474

5

Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development.

Göke J, Jung M, Behrens S, Chavez L, O'Keeffe S, Timmermann B, Lehrach H, Adjaye J, Vingron M. Göke J, et al. Among authors: lehrach h. PLoS Comput Biol. 2011 Dec;7(12):e1002304. doi: 10.1371/journal.pcbi.1002304. Epub 2011 Dec 22. PLoS Comput Biol. 2011. PMID: 22215994 Free PMC article.

6

DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer.

Grimm C, Chavez L, Vilardell M, Farrall AL, Tierling S, Böhm JW, Grote P, Lienhard M, Dietrich J, Timmermann B, Walter J, Schweiger MR, Lehrach H, Herwig R, Herrmann BG, Morkel M. Grimm C, et al. Among authors: lehrach h. PLoS Genet. 2013;9(2):e1003250. doi: 10.1371/journal.pgen.1003250. Epub 2013 Feb 7. PLoS Genet. 2013. PMID: 23408899 Free PMC article.

7

Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.

Mertes F, Lichtner B, Kuhl H, Blattner M, Otte J, Wruck W, Timmermann B, Lehrach H, Adjaye J. Mertes F, et al. Among authors: lehrach h. BMC Genomics. 2015 Nov 12;16:925. doi: 10.1186/s12864-015-2025-z. BMC Genomics. 2015. PMID: 26564201 Free PMC article.

8

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.

Grasse S, Lienhard M, Frese S, Kerick M, Steinbach A, Grimm C, Hussong M, Rolff J, Becker M, Dreher F, Schirmer U, Boerno S, Ramisch A, Leschber G, Timmermann B, Grohé C, Lüders H, Vingron M, Fichtner I, Klein S, Odenthal M, Büttner R, Lehrach H, Sültmann H, Herwig R, Schweiger MR. Grasse S, et al. Among authors: lehrach h. Genome Med. 2018 Jul 20;10(1):55. doi: 10.1186/s13073-018-0562-1. Genome Med. 2018. PMID: 30029672 Free PMC article.

9

A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells.

Jung M, Peterson H, Chavez L, Kahlem P, Lehrach H, Vilo J, Adjaye J. Jung M, et al. Among authors: lehrach h. PLoS One. 2010 May 21;5(5):e10709. doi: 10.1371/journal.pone.0010709. PLoS One. 2010. PMID: 20505756 Free PMC article.

10

New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes.

Panopoulou G, Hennig S, Groth D, Krause A, Poustka AJ, Herwig R, Vingron M, Lehrach H. Panopoulou G, et al. Among authors: lehrach h. Genome Res. 2003 Jun;13(6A):1056-66. doi: 10.1101/gr.874803. Genome Res. 2003. PMID: 12799346 Free PMC article.

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