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Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.
Edwards SM, Evans DG, Hope Q, Norman AR, Barbachano Y, Bullock S, Kote-Jarai Z, Meitz J, Falconer A, Osin P, Fisher C, Guy M, Jhavar SG, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Forrest MS, Dearnaley DP, Ardern-Jones AT, Page EC, Easton DF, Eeles RA; UK Genetic Prostate Cancer Study Collaborators and BAUS Section of Oncology. Edwards SM, et al. Br J Cancer. 2010 Sep 7;103(6):918-24. doi: 10.1038/sj.bjc.6605822. Epub 2010 Aug 24. Br J Cancer. 2010. PMID: 20736950 Free PMC article.
Immunohistochemical expression of BRCA2 protein and allelic loss at the BRCA2 locus in prostate cancer. CRC/BPG UK Familial Prostate Cancer Study Collaborators.
Edwards SM, Dunsmuir WD, Gillett CE, Lakhani SR, Corbishley C, Young M, Kirby RS, Dearnaley DP, Dowe A, Ardern-Jones A, Kelly J, Spurr N, Barnes DM, Eeles RA. Edwards SM, et al. Int J Cancer. 1998 Sep 25;78(1):1-7. doi: 10.1002/(sici)1097-0215(19980925)78:1<1::aid-ijc1>3.0.co;2-u. Int J Cancer. 1998. PMID: 9724085
Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group.
Dunsmuir WD, Edwards SM, Lakhani SR, Young M, Corbishley C, Kirby RS, Dearnaley DP, Dowe A, Ardern-Jones A, Kelly J, Eeles RA. Dunsmuir WD, et al. Among authors: edwards sm. Br J Cancer. 1998 Dec;78(11):1430-3. doi: 10.1038/bjc.1998.703. Br J Cancer. 1998. PMID: 9836474 Free PMC article.
BCL10 is rarely mutated in human prostate carcinoma, small-cell lung cancer, head and neck tumours, renal carcinoma and sarcomas. MPT Collaborators, St George's Hospital Collaborators.
Gill S, Broni J, Jefferies S, Osin P, Kovacs G, Maitland NJ, Eeles R, Edwards SM, Dyer MJ, Willis TG, Cooper CS. Gill S, et al. Among authors: edwards sm. Br J Cancer. 1999 Jul;80(10):1565-8. doi: 10.1038/sj.bjc.6690561. Br J Cancer. 1999. PMID: 10408398 Free PMC article.
No evidence of germline PTEN mutations in familial prostate cancer.
Forrest MS, Edwards SM, Hamoudi RA, Dearnaley DP, Arden-Jones A, Dowe A, Murkin A, Kelly J, Teare MD, Easton DF, Knowles MA, Bishop DT, Eeles RA. Forrest MS, et al. Among authors: edwards sm. J Med Genet. 2000 Mar;37(3):210-2. doi: 10.1136/jmg.37.3.210. J Med Genet. 2000. PMID: 10777362 Free PMC article. No abstract available.
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
Gayther SA, de Foy KA, Harrington P, Pharoah P, Dunsmuir WD, Edwards SM, Gillett C, Ardern-Jones A, Dearnaley DP, Easton DF, Ford D, Shearer RJ, Kirby RS, Dowe AL, Kelly J, Stratton MR, Ponder BA, Barnes D, Eeles RA. Gayther SA, et al. Among authors: edwards sm. Cancer Res. 2000 Aug 15;60(16):4513-8. Cancer Res. 2000. PMID: 10969800
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