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Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors.
McBride DJ, Orpana AK, Sotiriou C, Joensuu H, Stephens PJ, Mudie LJ, Hämäläinen E, Stebbings LA, Andersson LC, Flanagan AM, Durbecq V, Ignatiadis M, Kallioniemi O, Heckman CA, Alitalo K, Edgren H, Futreal PA, Stratton MR, Campbell PJ. McBride DJ, et al. Among authors: alitalo k. Genes Chromosomes Cancer. 2010 Nov;49(11):1062-9. doi: 10.1002/gcc.20815. Genes Chromosomes Cancer. 2010. PMID: 20725990 Free PMC article.
VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors.
Petrova TV, Bono P, Holnthoner W, Chesnes J, Pytowski B, Sihto H, Laakkonen P, Heikkilä P, Joensuu H, Alitalo K. Petrova TV, et al. Among authors: alitalo k. Cancer Cell. 2008 Jun;13(6):554-6. doi: 10.1016/j.ccr.2008.04.022. Cancer Cell. 2008. PMID: 18538738 Free article. No abstract available.
Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
Sugiyama N, Varjosalo M, Meller P, Lohi J, Hyytiäinen M, Kilpinen S, Kallioniemi O, Ingvarsen S, Engelholm LH, Taipale J, Alitalo K, Keski-Oja J, Lehti K. Sugiyama N, et al. Among authors: alitalo k. Cancer Res. 2010 Oct 15;70(20):7851-61. doi: 10.1158/0008-5472.CAN-10-1223. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876804
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.
Holopainen T, López-Alpuche V, Zheng W, Heljasvaara R, Jones D, He Y, Tvorogov D, D'Amico G, Wiener Z, Andersson LC, Pihlajaniemi T, Min W, Alitalo K. Holopainen T, et al. Among authors: alitalo k. Cancer Res. 2012 Jul 15;72(14):3512-21. doi: 10.1158/0008-5472.CAN-11-1070. Epub 2012 May 16. Cancer Res. 2012. PMID: 22593188
Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma.
Roos-Mattila M, Kallio P, Luck TJ, Polso M, Kumari R, Mikkonen P, Välimäki K, Malmstedt M, Ellonen P, Pellinen T, Heckman CA, Mustonen H, Puolakkainen PA, Alitalo K, Kallioniemi O, Mirtti T, Rannikko AS, Pietiäinen VM, Seppänen HE. Roos-Mattila M, et al. Among authors: alitalo k. Commun Biol. 2024 Oct 20;7(1):1355. doi: 10.1038/s42003-024-07004-9. Commun Biol. 2024. PMID: 39427059 Free PMC article.
725 results