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An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer.
Morse MA, Hobeika AC, Osada T, Berglund P, Hubby B, Negri S, Niedzwiecki D, Devi GR, Burnett BK, Clay TM, Smith J, Lyerly HK. Morse MA, et al. Among authors: clay tm. J Clin Invest. 2010 Sep;120(9):3234-41. doi: 10.1172/JCI42672. Epub 2010 Aug 2. J Clin Invest. 2010. PMID: 20679728 Free PMC article.
Immune signatures predict prognosis in localized cancer.
Hsu DS, Kim MK, Balakumaran BS, Acharya CR, Anders CK, Clay T, Lyerly HK, Drake CG, Morse MA, Febbo PG. Hsu DS, et al. Cancer Invest. 2010 Aug;28(7):765-73. doi: 10.3109/07357900903095755. Cancer Invest. 2010. PMID: 20569070 Free PMC article.
Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects.
Osada T, Berglund P, Morse MA, Hubby B, Lewis W, Niedzwiecki D, Yang XY, Hobeika A, Burnett B, Devi GR, Clay TM, Smith J, Kim Lyerly H. Osada T, et al. Among authors: clay tm. Cancer Immunol Immunother. 2012 Nov;61(11):1941-51. doi: 10.1007/s00262-012-1248-y. Epub 2012 Apr 10. Cancer Immunol Immunother. 2012. PMID: 22488274 Free PMC article.
Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients.
Morse MA, Chaudhry A, Gabitzsch ES, Hobeika AC, Osada T, Clay TM, Amalfitano A, Burnett BK, Devi GR, Hsu DS, Xu Y, Balcaitis S, Dua R, Nguyen S, Balint JP Jr, Jones FR, Lyerly HK. Morse MA, et al. Among authors: clay tm. Cancer Immunol Immunother. 2013 Aug;62(8):1293-301. doi: 10.1007/s00262-013-1400-3. Epub 2013 Apr 30. Cancer Immunol Immunother. 2013. PMID: 23624851 Free PMC article. Clinical Trial.
Recent developments in therapeutic cancer vaccines.
Morse MA, Chui S, Hobeika A, Lyerly HK, Clay T. Morse MA, et al. Nat Clin Pract Oncol. 2005 Feb;2(2):108-13. doi: 10.1038/ncponc0098. Nat Clin Pract Oncol. 2005. PMID: 16264883 Review.
Current immunotherapeutic strategies in colon cancer.
Morse M, Langer L, Starodub A, Hobeika A, Clay T, Lyerly HK. Morse M, et al. Surg Oncol Clin N Am. 2007 Oct;16(4):873-900, x. doi: 10.1016/j.soc.2007.07.005. Surg Oncol Clin N Am. 2007. PMID: 18022550 Review.
118 results