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Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
Am J Physiol Renal Physiol. 2010 Oct;299(4):F758-66. doi: 10.1152/ajprenal.00259.2010. Epub 2010 Jul 28.
Am J Physiol Renal Physiol. 2010.
PMID: 20668096
Free article.
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
Erbanová M, Thumová M, Husková Z, Vanecková I, Vanourková Z, Mullins JJ, Kramer HJ, Bürgelová M, Rakusan D, Cervenka L.
Erbanová M, et al. Among authors: rakusan d.
J Hypertens. 2009 Mar;27(3):575-86. doi: 10.1097/hjh.0b013e32831cbd5a.
J Hypertens. 2009.
PMID: 19330918
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Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Kujal P, Chábová VČ, Vernerová Z, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Vaňourková Z, Husková Z, Opočenský M, Skaroupková P, Schejbalová S, Kramer HJ, Rakušan D, Malý J, Netuka I, Vaněčková I, Kopkan L, Cervenka L.
Kujal P, et al. Among authors: rakusan d.
Clin Exp Pharmacol Physiol. 2010 Dec;37(12):1159-69. doi: 10.1111/j.1440-1681.2010.05453.x.
Clin Exp Pharmacol Physiol. 2010.
PMID: 20880190
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Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.
Rakušan D, Bürgelová M, Vaněčková I, Vaňourková Z, Husková Z, Skaroupková P, Mrázová I, Opočenský M, Kramer HJ, Netuka I, Malý J, Alenina N, Bader M, Santos RA, Cervenka L.
Rakušan D, et al.
Kidney Blood Press Res. 2010;33(6):476-88. doi: 10.1159/000320689. Epub 2010 Nov 10.
Kidney Blood Press Res. 2010.
PMID: 21071955
Free article.
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