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Page 1
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Melrose HL, Dächsel JC, Behrouz B, Lincoln SJ, Yue M, Hinkle KM, Kent CB, Korvatska E, Taylor JP, Witten L, Liang YQ, Beevers JE, Boules M, Dugger BN, Serna VA, Gaukhman A, Yu X, Castanedes-Casey M, Braithwaite AT, Ogholikhan S, Yu N, Bass D, Tyndall G, Schellenberg GD, Dickson DW, Janus C, Farrer MJ. Melrose HL, et al. Among authors: braithwaite at. Neurobiol Dis. 2010 Dec;40(3):503-17. doi: 10.1016/j.nbd.2010.07.010. Epub 2010 Jul 24. Neurobiol Dis. 2010. PMID: 20659558 Free PMC article.
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice.
Winner B, Melrose HL, Zhao C, Hinkle KM, Yue M, Kent C, Braithwaite AT, Ogholikhan S, Aigner R, Winkler J, Farrer MJ, Gage FH. Winner B, et al. Among authors: braithwaite at. Neurobiol Dis. 2011 Mar;41(3):706-16. doi: 10.1016/j.nbd.2010.12.008. Epub 2010 Dec 16. Neurobiol Dis. 2011. PMID: 21168496 Free PMC article.
In vivo silencing of alpha-synuclein using naked siRNA.
Lewis J, Melrose H, Bumcrot D, Hope A, Zehr C, Lincoln S, Braithwaite A, He Z, Ogholikhan S, Hinkle K, Kent C, Toudjarska I, Charisse K, Braich R, Pandey RK, Heckman M, Maraganore DM, Crook J, Farrer MJ. Lewis J, et al. Mol Neurodegener. 2008 Nov 1;3:19. doi: 10.1186/1750-1326-3-19. Mol Neurodegener. 2008. PMID: 18976489 Free PMC article.
Genomic investigation of alpha-synuclein multiplication and parkinsonism.
Ross OA, Braithwaite AT, Skipper LM, Kachergus J, Hulihan MM, Middleton FA, Nishioka K, Fuchs J, Gasser T, Maraganore DM, Adler CH, Larvor L, Chartier-Harlin MC, Nilsson C, Langston JW, Gwinn K, Hattori N, Farrer MJ. Ross OA, et al. Among authors: braithwaite at. Ann Neurol. 2008 Jun;63(6):743-50. doi: 10.1002/ana.21380. Ann Neurol. 2008. PMID: 18571778 Free PMC article.
Rapid neutrophil mobilization by VCAM-1+ endothelial cell-derived extracellular vesicles.
Akbar N, Braithwaite AT, Corr EM, Koelwyn GJ, van Solingen C, Cochain C, Saliba AE, Corbin A, Pezzolla D, Møller Jørgensen M, Bæk R, Edgar L, De Villiers C, Gunadasa-Rohling M, Banerjee A, Paget D, Lee C, Hogg E, Costin A, Dhaliwal R, Johnson E, Krausgruber T, Riepsaame J, Melling GE, Shanmuganathan M; Oxford Acute Myocardial Infarction Study (OxAMI); Bock C, Carter DRF, Channon KM, Riley PR, Udalova IA, Moore KJ, Anthony DC, Choudhury RP. Akbar N, et al. Among authors: braithwaite at. Cardiovasc Res. 2023 Mar 17;119(1):236-251. doi: 10.1093/cvr/cvac012. Cardiovasc Res. 2023. PMID: 35134856 Free PMC article.
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.
Edgar L, Akbar N, Braithwaite AT, Krausgruber T, Gallart-Ayala H, Bailey J, Corbin AL, Khoyratty TE, Chai JT, Alkhalil M, Rendeiro AF, Ziberna K, Arya R, Cahill TJ, Bock C, Laurencikiene J, Crabtree MJ, Lemieux ME, Riksen NP, Netea MG, Wheelock CE, Channon KM, Rydén M, Udalova IA, Carnicer R, Choudhury RP. Edgar L, et al. Among authors: braithwaite at. Circulation. 2021 Sep 21;144(12):961-982. doi: 10.1161/CIRCULATIONAHA.120.046464. Epub 2021 Jul 13. Circulation. 2021. PMID: 34255973 Free PMC article.
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Zawia A, Arnold ND, West L, Pickworth JA, Turton H, Iremonger J, Braithwaite AT, Cañedo J, Johnston SA, Thompson AAR, Miller G, Lawrie A. Zawia A, et al. Among authors: braithwaite at. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):430-445. doi: 10.1161/ATVBAHA.120.314639. Epub 2020 Nov 5. Arterioscler Thromb Vasc Biol. 2021. PMID: 33147993 Free PMC article.
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
Arnold ND, Pickworth JA, West LE, Dawson S, Carvalho JA, Casbolt H, Braithwaite AT, Iremonger J, Renshall L, Germaschewski V, McCourt M, Bland-Ward P, Kowash H, Hameed AG, Rothman AMK, Frid MG, Roger Thompson AA, Evans HR, Southwood M, Morrell NW, Crossman DC, Whyte MKB, Stenmark KR, Newman CM, Kiely DG, Francis SE, Lawrie A. Arnold ND, et al. Among authors: braithwaite at. Nat Commun. 2019 Nov 15;10(1):5183. doi: 10.1038/s41467-019-13139-9. Nat Commun. 2019. PMID: 31729368 Free PMC article.
Divergent Roles for TRAIL in Lung Diseases.
Braithwaite AT, Marriott HM, Lawrie A. Braithwaite AT, et al. Front Med (Lausanne). 2018 Jul 27;5:212. doi: 10.3389/fmed.2018.00212. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30101145 Free PMC article. Review.