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Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
Johansen CT, Wang J, Lanktree MB, Cao H, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Hegele RA. Johansen CT, et al. Among authors: kennedy ba. Nat Genet. 2010 Aug;42(8):684-7. doi: 10.1038/ng.628. Epub 2010 Jul 25. Nat Genet. 2010. PMID: 20657596 Free PMC article.
Polygenic determinants of severe hypertriglyceridemia.
Wang J, Ban MR, Zou GY, Cao H, Lin T, Kennedy BA, Anand S, Yusuf S, Huff MW, Pollex RL, Hegele RA. Wang J, et al. Among authors: kennedy ba. Hum Mol Genet. 2008 Sep 15;17(18):2894-9. doi: 10.1093/hmg/ddn188. Epub 2008 Jul 1. Hum Mol Genet. 2008. PMID: 18596051
An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia.
Johansen CT, Wang J, Lanktree MB, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Cao H, Hegele RA. Johansen CT, et al. Among authors: kennedy ba. Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1916-26. doi: 10.1161/ATVBAHA.111.226365. Epub 2011 May 19. Arterioscler Thromb Vasc Biol. 2011. PMID: 21597005 Free PMC article.
Common low-density lipoprotein receptor p.G116S variant has a large effect on plasma low-density lipoprotein cholesterol in circumpolar inuit populations.
Dubé JB, Wang J, Cao H, McIntyre AD, Johansen CT, Hopkins SE, Stringer R, Hosseinzadeh S, Kennedy BA, Ban MR, Young TK, Connelly PW, Dewailly E, Bjerregaard P, Boyer BB, Hegele RA. Dubé JB, et al. Among authors: kennedy ba. Circ Cardiovasc Genet. 2015 Feb;8(1):100-5. doi: 10.1161/CIRCGENETICS.114.000646. Epub 2014 Nov 20. Circ Cardiovasc Genet. 2015. PMID: 25414273 Free PMC article. Clinical Trial.
30 results