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The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms.
Hapfelmeier S, Stecher B, Barthel M, Kremer M, Müller AJ, Heikenwalder M, Stallmach T, Hensel M, Pfeffer K, Akira S, Hardt WD. Hapfelmeier S, et al. Among authors: heikenwalder m. J Immunol. 2005 Feb 1;174(3):1675-85. doi: 10.4049/jimmunol.174.3.1675. J Immunol. 2005. PMID: 15661931
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis.
Hapfelmeier S, Müller AJ, Stecher B, Kaiser P, Barthel M, Endt K, Eberhard M, Robbiani R, Jacobi CA, Heikenwalder M, Kirschning C, Jung S, Stallmach T, Kremer M, Hardt WD. Hapfelmeier S, et al. Among authors: heikenwalder m. J Exp Med. 2008 Feb 18;205(2):437-50. doi: 10.1084/jem.20070633. Epub 2008 Feb 11. J Exp Med. 2008. PMID: 18268033 Free PMC article.
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.
Seleznik GM, Reding T, Romrig F, Saito Y, Mildner A, Segerer S, Sun LK, Regenass S, Lech M, Anders HJ, McHugh D, Kumagi T, Hiasa Y, Lackner C, Haybaeck J, Angst E, Perren A, Balmer ML, Slack E, MacPherson A, Manz MG, Weber A, Browning JL, Arkan MC, Rülicke T, Aguzzi A, Prinz M, Graf R, Heikenwalder M. Seleznik GM, et al. Among authors: heikenwalder m. Gastroenterology. 2012 Nov;143(5):1361-1374. doi: 10.1053/j.gastro.2012.07.112. Epub 2012 Aug 2. Gastroenterology. 2012. PMID: 22863765 Free article.
The maternal microbiota drives early postnatal innate immune development.
Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ. Gomez de Agüero M, et al. Among authors: heikenwalder m. Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571. Science. 2016. PMID: 26989247
The Liver at the Nexus of Host-Microbial Interactions.
Macpherson AJ, Heikenwalder M, Ganal-Vonarburg SC. Macpherson AJ, et al. Among authors: heikenwalder m. Cell Host Microbe. 2016 Nov 9;20(5):561-571. doi: 10.1016/j.chom.2016.10.016. Cell Host Microbe. 2016. PMID: 27832587 Free article. Review.
MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice.
Healy ME, Boege Y, Hodder MC, Böhm F, Malehmir M, Scherr AL, Jetzer J, Chan LK, Parrotta R, Jacobs K, Clerbaux LA, Kreutzer S, Campbell A, Gilchrist E, Gilroy K, Rodewald AK, Honcharova-Biletska H, Schimmer R, Vélez K, Büeler S, Cammareri P, Kalna G, Wenning AS, McCoy KD, Gomez de Agüero M, Schulze-Bergkamen H, Klose CSN, Unger K, Macpherson AJ, Moor AE, Köhler B, Sansom OJ, Heikenwälder M, Weber A. Healy ME, et al. Among authors: heikenwalder m. Gastroenterology. 2020 Jul;159(1):183-199. doi: 10.1053/j.gastro.2020.03.017. Epub 2020 Mar 14. Gastroenterology. 2020. PMID: 32179094 Free PMC article.
Mucosal or systemic microbiota exposures shape the B cell repertoire.
Li H, Limenitakis JP, Greiff V, Yilmaz B, Schären O, Urbaniak C, Zünd M, Lawson MAE, Young ID, Rupp S, Heikenwälder M, McCoy KD, Hapfelmeier S, Ganal-Vonarburg SC, Macpherson AJ. Li H, et al. Among authors: heikenwalder m. Nature. 2020 Aug;584(7820):274-278. doi: 10.1038/s41586-020-2564-6. Epub 2020 Aug 5. Nature. 2020. PMID: 32760003
343 results