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Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors.
Bannwart LM, Carter DS, Cai HY, Choy JC, Greenhouse R, Jaime-Figueroa S, Iyer PS, Lin CJ, Lee EK, Lucas MC, Lynch SM, Madera AM, Moore A, Ozboya K, Raptova L, Roetz R, Schoenfeld RC, Stein KA, Steiner S, Villa M, Weikert RJ, Zhai Y. Bannwart LM, et al. Among authors: cai hy. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6062-6. doi: 10.1016/j.bmcl.2008.10.025. Epub 2008 Oct 11. Bioorg Med Chem Lett. 2008. PMID: 18954985
Novel, achiral aminoheterocycles as selective monoamine reuptake inhibitors.
Lucas MC, Carter DS, Cai HY, Lee EK, Schoenfeld RC, Steiner S, Villa M, Weikert RJ, Iyer PS. Lucas MC, et al. Among authors: cai hy. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4630-3. doi: 10.1016/j.bmcl.2009.06.076. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19592243
Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain.
Lucas MC, Weikert RJ, Carter DS, Cai HY, Greenhouse R, Iyer PS, Lin CJ, Lee EK, Madera AM, Moore A, Ozboya K, Schoenfeld RC, Steiner S, Zhai Y, Lynch SM. Lucas MC, et al. Among authors: cai hy. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5559-66. doi: 10.1016/j.bmcl.2010.07.020. Epub 2010 Aug 4. Bioorg Med Chem Lett. 2010. PMID: 20691589
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.
Pero JE, Mueller EA, Adams AM, Adolph RS, Bagchi P, Balce D, Bantscheff M, Barauskas O, Bartha I, Bohan D, Cai H, Carabajal E, Cassidy J, Cato M, Chaudhary KW, Chen D, Chen YP, Colas C, Darwech I, Eberl HC, Fernandez B, Gordon E, Grosse J, Hansen J, Hetzler B, Hwang S, Jeyasingh S, Kowalski B, Lehmann S, Lo G, McAllaster M, McHugh C, Momont C, Newby Z, Nigro M, Oladunni F, Pannirselvam M, Park A, Pearson N, Peat AJ, Plastridge B, Ranjan R, Safabakhsh P, Shapiro ND, Soriaga L, Stokes N, Sweeney D, Talecki L, Telenti A, Terrell A, Tse W, Wang L, Wang S, Wedel L, Werner T, Dalmas Wilk D, Yim S, Zhou J. Pero JE, et al. J Med Chem. 2024 Aug 22;67(16):14586-14608. doi: 10.1021/acs.jmedchem.4c01402. Epub 2024 Aug 13. J Med Chem. 2024. PMID: 39136957
223 results