Ryffel GU - Search Results

1

Novel monogenic diabetes mutations in the P2 promoter of the HNF4A gene are associated with impaired function in vitro.

Wirsing A, Johnstone KA, Harries LW, Ellard S, Ryffel GU, Stanik J, Gasperikova D, Klimes I, Murphy R. Wirsing A, et al. Among authors: ryffel gu. Diabet Med. 2010 Jun;27(6):631-5. doi: 10.1111/j.1464-5491.2010.03003.x. Diabet Med. 2010. PMID: 20546279

2

A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.

Wirsing A, Senkel S, Klein-Hitpass L, Ryffel GU. Wirsing A, et al. Among authors: ryffel gu. PLoS One. 2011;6(11):e27438. doi: 10.1371/journal.pone.0027438. Epub 2011 Nov 30. PLoS One. 2011. PMID: 22140441 Free PMC article.

3

A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.

Thomas H, Jaschkowitz K, Bulman M, Frayling TM, Mitchell SM, Roosen S, Lingott-Frieg A, Tack CJ, Ellard S, Ryffel GU, Hattersley AT. Thomas H, et al. Among authors: ryffel gu. Hum Mol Genet. 2001 Sep 15;10(19):2089-97. doi: 10.1093/hmg/10.19.2089. Hum Mol Genet. 2001. PMID: 11590126

4

Evidence for haploinsufficiency of the human HNF1alpha gene revealed by functional characterization of MODY3-associated mutations.

Thomas H, Badenberg B, Bulman M, Lemm I, Lausen J, Kind L, Roosen S, Ellard S, Hattersley AT, Ryffel GU. Thomas H, et al. Among authors: ryffel gu. Biol Chem. 2002 Nov;383(11):1691-700. doi: 10.1515/BC.2002.190. Biol Chem. 2002. PMID: 12530534

5

Distinct molecular and morphogenetic properties of mutations in the human HNF1beta gene that lead to defective kidney development.

Bohn S, Thomas H, Turan G, Ellard S, Bingham C, Hattersley AT, Ryffel GU. Bohn S, et al. Among authors: ryffel gu. J Am Soc Nephrol. 2003 Aug;14(8):2033-41. doi: 10.1097/01.asn.0000078808.70309.c4. J Am Soc Nephrol. 2003. PMID: 12874457

6

HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells.

Grigo K, Wirsing A, Lucas B, Klein-Hitpass L, Ryffel GU. Grigo K, et al. Among authors: ryffel gu. Biol Chem. 2008 Feb;389(2):179-87. doi: 10.1515/BC.2008.011. Biol Chem. 2008. PMID: 18163890

7

The mutated human gene encoding hepatocyte nuclear factor 1beta inhibits kidney formation in developing Xenopus embryos.

Wild W, Pogge von Strandmann E, Nastos A, Senkel S, Lingott-Frieg A, Bulman M, Bingham C, Ellard S, Hattersley AT, Ryffel GU. Wild W, et al. Among authors: ryffel gu. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4695-700. doi: 10.1073/pnas.080010897. Proc Natl Acad Sci U S A. 2000. PMID: 10758154 Free PMC article.

8

HNF1B mutations associate with hypomagnesemia and renal magnesium wasting.

Adalat S, Woolf AS, Johnstone KA, Wirsing A, Harries LW, Long DA, Hennekam RC, Ledermann SE, Rees L, van't Hoff W, Marks SD, Trompeter RS, Tullus K, Winyard PJ, Cansick J, Mushtaq I, Dhillon HK, Bingham C, Edghill EL, Shroff R, Stanescu H, Ryffel GU, Ellard S, Bockenhauer D. Adalat S, et al. Among authors: ryffel gu. J Am Soc Nephrol. 2009 May;20(5):1123-31. doi: 10.1681/ASN.2008060633. Epub 2009 Apr 23. J Am Soc Nephrol. 2009. PMID: 19389850 Free PMC article.

9

Transcription factor HNF1beta and novel partners affect nephrogenesis.

Dudziak K, Mottalebi N, Senkel S, Edghill EL, Rosengarten S, Roose M, Bingham C, Ellard S, Ryffel GU. Dudziak K, et al. Among authors: ryffel gu. Kidney Int. 2008 Jul;74(2):210-7. doi: 10.1038/ki.2008.149. Epub 2008 Apr 16. Kidney Int. 2008. PMID: 18418350 Free article.

10

Conditional expression of hepatocyte nuclear factor-1beta, the maturity-onset diabetes of the young-5 gene product, influences the viability and functional competence of pancreatic beta-cells.

Welters HJ, Senkel S, Klein-Hitpass L, Erdmann S, Thomas H, Harries LW, Pearson ER, Bingham C, Hattersley AT, Ryffel GU, Morgan NG. Welters HJ, et al. Among authors: ryffel gu. J Endocrinol. 2006 Jul;190(1):171-81. doi: 10.1677/joe.1.06768. J Endocrinol. 2006. PMID: 16837621

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

118 results

Search Page