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The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.
Wei Y, Kadia T, Tong W, Zhang M, Jia Y, Yang H, Hu Y, Tambaro FP, Viallet J, O'Brien S, Garcia-Manero G. Wei Y, et al. Among authors: jia y. Clin Cancer Res. 2010 Aug 1;16(15):3923-32. doi: 10.1158/1078-0432.CCR-10-0032. Epub 2010 Jun 10. Clin Cancer Res. 2010. PMID: 20538760 Free PMC article.
Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion.
Cabrero M, Yu Y, Verma A, Yang H, Colla S, Jia Y, Zheng H, Bohannan Z, Ganan-Gomez I, Futreal A, Takahashi K, Chin L, Kantarjian H, Pellagatti A, Bowman T, Boultwood J, Garcia-Manero G, Wei Y. Cabrero M, et al. Among authors: jia y. Br J Haematol. 2016 Apr;173(1):161-5. doi: 10.1111/bjh.13574. Epub 2015 Jun 24. Br J Haematol. 2016. PMID: 26105212 Free PMC article. No abstract available.
Low frequency of H3.3 mutations and upregulated DAXX expression in MDS.
Attieh Y, Geng QR, Dinardo CD, Zheng H, Jia Y, Fang ZH, Gañán-Gómez I, Yang H, Wei Y, Kantarjian H, Garcia-Manero G. Attieh Y, et al. Among authors: jia y. Blood. 2013 May 9;121(19):4009-11. doi: 10.1182/blood-2012-11-466714. Blood. 2013. PMID: 23660862 Free article. No abstract available.
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