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Deferasirox is a powerful NF-kappaB inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging.
Messa E, Carturan S, Maffè C, Pautasso M, Bracco E, Roetto A, Messa F, Arruga F, Defilippi I, Rosso V, Zanone C, Rotolo A, Greco E, Pellegrino RM, Alberti D, Saglio G, Cilloni D. Messa E, et al. Among authors: greco e. Haematologica. 2010 Aug;95(8):1308-16. doi: 10.3324/haematol.2009.016824. Epub 2010 Jun 9. Haematologica. 2010. PMID: 20534700 Free PMC article.
WITHDRAWN: Proteinase 3 (PR3) gene is highly expressed in CBF leukemias and codes for a protein with abnormal nuclear localization that confers drug sensitivity.
Cilloni D, Carturan S, Maffè C, Messa F, Arruga F, Messa E, Pradotto M, Pautasso M, Zanone C, Fornaciari P, Defilippi I, Rotolo A, Greco E, Iacobucci I, Martinelli G, Lo-Coco F, Bracco E, Saglio G. Cilloni D, et al. Among authors: greco e. Leukemia. 2010 Jan 14. doi: 10.1038/leu.2009.207. Online ahead of print. Leukemia. 2010. PMID: 20072158
Platelets and Multi-Organ Failure in Sepsis.
Greco E, Lupia E, Bosco O, Vizio B, Montrucchio G. Greco E, et al. Int J Mol Sci. 2017 Oct 20;18(10):2200. doi: 10.3390/ijms18102200. Int J Mol Sci. 2017. PMID: 29053592 Free PMC article. Review.
Prophylaxis of venous thromboembolism in elderly patients with multimorbidity.
Marcucci M, Iorio A, Nobili A, Tettamanti M, Pasina L, Djade CD, Marengoni A, Salerno F, Corrao S, Mannucci PM; REPOSI (REgistro POliterapie Società Italiana di Medicina Interna) Investigators. Marcucci M, et al. Intern Emerg Med. 2013 Sep;8(6):509-20. doi: 10.1007/s11739-013-0944-8. Epub 2013 May 8. Intern Emerg Med. 2013. PMID: 23653407 Free article.
738 results