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Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP. Rauch A, et al. Among authors: tuckermann jp. Cell Metab. 2010 Jun 9;11(6):517-31. doi: 10.1016/j.cmet.2010.05.005. Cell Metab. 2010. PMID: 20519123 Free article.
Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse.
Tuckermann JP, Pittois K, Partridge NC, Merregaert J, Angel P. Tuckermann JP, et al. J Bone Miner Res. 2000 Jul;15(7):1257-65. doi: 10.1359/jbmr.2000.15.7.1257. J Bone Miner Res. 2000. PMID: 10893674 Free article.
A role for endogenous glucocorticoids in wound repair.
Grose R, Werner S, Kessler D, Tuckermann J, Huggel K, Durka S, Reichardt HM, Werner S. Grose R, et al. EMBO Rep. 2002 Jun;3(6):575-82. doi: 10.1093/embo-reports/kvf119. Epub 2002 May 24. EMBO Rep. 2002. PMID: 12034758 Free PMC article.
178 results