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Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP. Rauch A, et al. Among authors: ostermay s. Cell Metab. 2010 Jun 9;11(6):517-31. doi: 10.1016/j.cmet.2010.05.005. Cell Metab. 2010. PMID: 20519123 Free article.
Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis.
Liu P, Lee S, Knoll J, Rauch A, Ostermay S, Luther J, Malkusch N, Lerner UH, Zaiss MM, Neven M, Wittig R, Rauner M, David JP, Bertolino P, Zhang CX, Tuckermann JP. Liu P, et al. Among authors: ostermay s. Cell Death Differ. 2017 Apr;24(4):672-682. doi: 10.1038/cdd.2016.165. Epub 2017 Jan 20. Cell Death Differ. 2017. PMID: 28106886 Free PMC article.