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Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.
Peterson TE, Kirkpatrick ND, Huang Y, Farrar CT, Marijt KA, Kloepper J, Datta M, Amoozgar Z, Seano G, Jung K, Kamoun WS, Vardam T, Snuderl M, Goveia J, Chatterjee S, Batista A, Muzikansky A, Leow CC, Xu L, Batchelor TT, Duda DG, Fukumura D, Jain RK. Peterson TE, et al. Among authors: kirkpatrick nd. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4470-5. doi: 10.1073/pnas.1525349113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044097 Free PMC article.
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.
Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK. Snuderl M, et al. Among authors: kirkpatrick nd. Cell. 2013 Feb 28;152(5):1065-76. doi: 10.1016/j.cell.2013.01.036. Cell. 2013. PMID: 23452854 Free PMC article.
Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression.
Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK. Goel S, et al. Among authors: kirkpatrick nd. J Natl Cancer Inst. 2013 Aug 21;105(16):1188-201. doi: 10.1093/jnci/djt164. Epub 2013 Jul 30. J Natl Cancer Inst. 2013. PMID: 23899555 Free PMC article.
Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.
Kloepper J, Riedemann L, Amoozgar Z, Seano G, Susek K, Yu V, Dalvie N, Amelung RL, Datta M, Song JW, Askoxylakis V, Taylor JW, Lu-Emerson C, Batista A, Kirkpatrick ND, Jung K, Snuderl M, Muzikansky A, Stubenrauch KG, Krieter O, Wakimoto H, Xu L, Munn LL, Duda DG, Fukumura D, Batchelor TT, Jain RK. Kloepper J, et al. Among authors: kirkpatrick nd. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4476-81. doi: 10.1073/pnas.1525360113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044098 Free PMC article.
Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.
Ager EI, Kozin SV, Kirkpatrick ND, Seano G, Kodack DP, Askoxylakis V, Huang Y, Goel S, Snuderl M, Muzikansky A, Finkelstein DM, Dransfield DT, Devy L, Boucher Y, Fukumura D, Jain RK. Ager EI, et al. Among authors: kirkpatrick nd. J Natl Cancer Inst. 2015 Feb 20;107(4):djv017. doi: 10.1093/jnci/djv017. Print 2015 Apr. J Natl Cancer Inst. 2015. PMID: 25710962 Free PMC article.
28 results