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Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway.
Balloy V, Sallenave JM, Wu Y, Touqui L, Latgé JP, Si-Tahar M, Chignard M. Balloy V, et al. Among authors: sallenave jm. J Biol Chem. 2008 Nov 7;283(45):30513-21. doi: 10.1074/jbc.M803149200. Epub 2008 Aug 14. J Biol Chem. 2008. PMID: 18703508 Free PMC article.
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Motta JP, Magne L, Descamps D, Rolland C, Squarzoni-Dale C, Rousset P, Martin L, Cenac N, Balloy V, Huerre M, Fröhlich LF, Jenne D, Wartelle J, Belaaouaj A, Mas E, Vinel JP, Alric L, Chignard M, Vergnolle N, Sallenave JM. Motta JP, et al. Among authors: sallenave jm. Gastroenterology. 2011 Apr;140(4):1272-82. doi: 10.1053/j.gastro.2010.12.050. Epub 2011 Jan 1. Gastroenterology. 2011. PMID: 21199654
Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.
Descamps D, Le Gars M, Balloy V, Barbier D, Maschalidi S, Tohme M, Chignard M, Ramphal R, Manoury B, Sallenave JM. Descamps D, et al. Among authors: sallenave jm. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1619-24. doi: 10.1073/pnas.1108464109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22307620 Free PMC article.
Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway.
Barbier D, Garcia-Verdugo I, Pothlichet J, Khazen R, Descamps D, Rousseau K, Thornton D, Si-Tahar M, Touqui L, Chignard M, Sallenave JM. Barbier D, et al. Among authors: sallenave jm. Am J Respir Cell Mol Biol. 2012 Aug;47(2):149-57. doi: 10.1165/rcmb.2011-0405OC. Epub 2012 Mar 1. Am J Respir Cell Mol Biol. 2012. PMID: 22383584
108 results