Murphy MP - Search Results

1

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients.

Gane EJ, Weilert F, Orr DW, Keogh GF, Gibson M, Lockhart MM, Frampton CM, Taylor KM, Smith RA, Murphy MP. Gane EJ, et al. Among authors: murphy mp. Liver Int. 2010 Aug;30(7):1019-26. doi: 10.1111/j.1478-3231.2010.02250.x. Epub 2010 May 18. Liver Int. 2010. PMID: 20492507 Clinical Trial.

2

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease.

Snow BJ, Rolfe FL, Lockhart MM, Frampton CM, O'Sullivan JD, Fung V, Smith RA, Murphy MP, Taylor KM; Protect Study Group. Snow BJ, et al. Among authors: murphy mp. Mov Disord. 2010 Aug 15;25(11):1670-4. doi: 10.1002/mds.23148. Mov Disord. 2010. PMID: 20568096 Clinical Trial.

3

Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

Smith RA, Murphy MP. Smith RA, et al. Among authors: murphy mp. Ann N Y Acad Sci. 2010 Jul;1201:96-103. doi: 10.1111/j.1749-6632.2010.05627.x. Ann N Y Acad Sci. 2010. PMID: 20649545 Review.

4

Mitochondria-targeted antioxidants as therapies.

Smith RA, Murphy MP. Smith RA, et al. Among authors: murphy mp. Discov Med. 2011 Feb;11(57):106-14. Discov Med. 2011. PMID: 21356165 Free article. Review.

5

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

Murphy MP, Smith RA. Murphy MP, et al. Annu Rev Pharmacol Toxicol. 2007;47:629-56. doi: 10.1146/annurev.pharmtox.47.120505.105110. Annu Rev Pharmacol Toxicol. 2007. PMID: 17014364 Review.

6

Neonatal rat hypoxia-ischemia: Effect of the anti-oxidant mitoquinol, and S-PBN.

Hobbs CE, Murphy MP, Smith RA, Oorschot DE. Hobbs CE, et al. Among authors: murphy mp. Pediatr Int. 2008 Aug;50(4):481-8. doi: 10.1111/j.1442-200X.2008.02705.x. Pediatr Int. 2008. PMID: 18937752

7

Mitochondria-targeted small molecule therapeutics and probes.

Smith RA, Hartley RC, Murphy MP. Smith RA, et al. Among authors: murphy mp. Antioxid Redox Signal. 2011 Dec 15;15(12):3021-38. doi: 10.1089/ars.2011.3969. Epub 2011 Jun 6. Antioxid Redox Signal. 2011. PMID: 21395490 Review.

8

Drug delivery to mitochondria: the key to mitochondrial medicine.

Murphy MP, Smith RA. Murphy MP, et al. Adv Drug Deliv Rev. 2000 Mar 30;41(2):235-50. doi: 10.1016/s0169-409x(99)00069-1. Adv Drug Deliv Rev. 2000. PMID: 10699318 Review.

9

Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury.

Adlam VJ, Harrison JC, Porteous CM, James AM, Smith RA, Murphy MP, Sammut IA. Adlam VJ, et al. Among authors: murphy mp. FASEB J. 2005 Jul;19(9):1088-95. doi: 10.1096/fj.05-3718com. FASEB J. 2005. PMID: 15985532

10

Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity.

Maroz A, Anderson RF, Smith RA, Murphy MP. Maroz A, et al. Among authors: murphy mp. Free Radic Biol Med. 2009 Jan 1;46(1):105-9. doi: 10.1016/j.freeradbiomed.2008.09.033. Epub 2008 Oct 14. Free Radic Biol Med. 2009. PMID: 18977291

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