Ono K - Search Results

1

Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid beta-protein assembly and toxicity.

Ono K, Condron MM, Teplow DB. Ono K, et al. J Biol Chem. 2010 Jul 23;285(30):23186-97. doi: 10.1074/jbc.M109.086496. Epub 2010 May 7. J Biol Chem. 2010. PMID: 20452980 Free PMC article.

2

Cerebrospinal fluid of Alzheimer patients promotes beta-amyloid fibril formation in vitro.

Ono K, Noguchi M, Matsumoto Y, Yanase D, Iwasa K, Naiki H, Yamada M. Ono K, et al. Neurobiol Dis. 2005 Nov;20(2):233-40. doi: 10.1016/j.nbd.2005.03.005. Neurobiol Dis. 2005. PMID: 16242632

3

Estrogen has anti-amyloidogenic effects on Alzheimer's beta-amyloid fibrils in vitro.

Morinaga A, Hirohata M, Ono K, Yamada M. Morinaga A, et al. Among authors: ono k. Biochem Biophys Res Commun. 2007 Aug 3;359(3):697-702. doi: 10.1016/j.bbrc.2007.05.158. Epub 2007 Jun 4. Biochem Biophys Res Commun. 2007. PMID: 17559807

4

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.

Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM. Wang J, et al. Among authors: ono k. J Neurosci. 2008 Jun 18;28(25):6388-92. doi: 10.1523/JNEUROSCI.0364-08.2008. J Neurosci. 2008. PMID: 18562609 Free PMC article.

5

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity.

Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. Ono K, et al. J Biol Chem. 2008 Nov 21;283(47):32176-87. doi: 10.1074/jbc.M806154200. Epub 2008 Sep 24. J Biol Chem. 2008. PMID: 18815129 Free PMC article.

These studies showed that a commercially available grape seed polyphenolic extract, MegaNatural-AZ (MN), significantly attenuated AD-type cognitive deterioration and reduced cerebral amyloid deposition (Wang, J., Ho, L., Zhao, W., Ono, K., Rosensweig, C., Chen, L., …

These studies showed that a commercially available grape seed polyphenolic extract, MegaNatural-AZ (MN), significantly attenuated AD-type co …

6

Amyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.

Yamin G, Ono K, Inayathullah M, Teplow DB. Yamin G, et al. Among authors: ono k. Curr Pharm Des. 2008;14(30):3231-46. doi: 10.2174/138161208786404137. Curr Pharm Des. 2008. PMID: 19075703 Free PMC article. Review.

7

Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization.

Zhao W, Wang J, Ho L, Ono K, Teplow DB, Pasinetti GM. Zhao W, et al. Among authors: ono k. J Alzheimers Dis. 2009;16(1):49-57. doi: 10.3233/JAD-2009-0925. J Alzheimers Dis. 2009. PMID: 19158421

8

Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration.

Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM. Ho L, et al. Among authors: ono k. J Alzheimers Dis. 2009;16(1):59-72. doi: 10.3233/JAD-2009-0916. J Alzheimers Dis. 2009. PMID: 19158422 Free PMC article.

9

Structure-neurotoxicity relationships of amyloid beta-protein oligomers.

Ono K, Condron MM, Teplow DB. Ono K, et al. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14745-50. doi: 10.1073/pnas.0905127106. Epub 2009 Aug 12. Proc Natl Acad Sci U S A. 2009. PMID: 19706468 Free PMC article.

10

Cerebrospinal Fluid from Alzheimer's disease patients promotes amyloid beta-protein oligomerization.

Ikeda T, Ono K, Elashoff D, Condron MM, Noguchi-Shinohara M, Yoshita M, Teplow DB, Yamada M. Ikeda T, et al. Among authors: ono k. J Alzheimers Dis. 2010;21(1):81-6. doi: 10.3233/JAD-2010-100075. J Alzheimers Dis. 2010. PMID: 20413863

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