Hardingham GE - Search Results

1

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Hardingham GE, Patani R, Baxter P, Wyllie DJ, Chandran S. Hardingham GE, et al. Mol Neurobiol. 2010 Aug;42(1):97-102. doi: 10.1007/s12035-010-8136-2. Epub 2010 Apr 30. Mol Neurobiol. 2010. PMID: 20431962 Free PMC article.

2

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.

Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Papadia S, et al. Among authors: hardingham ge. Nat Neurosci. 2008 Apr;11(4):476-87. doi: 10.1038/nn2071. Epub 2008 Mar 23. Nat Neurosci. 2008. PMID: 18344994 Free PMC article.

3

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.

Martel MA, Wyllie DJ, Hardingham GE. Martel MA, et al. Among authors: hardingham ge. Neuroscience. 2009 Jan 12;158(1):334-43. doi: 10.1016/j.neuroscience.2008.01.080. Epub 2008 Mar 4. Neuroscience. 2009. PMID: 18378405 Free PMC article.

4

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

Soriano FX, Léveillé F, Papadia S, Higgins LG, Varley J, Baxter P, Hayes JD, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurochem. 2008 Oct;107(2):533-43. doi: 10.1111/j.1471-4159.2008.05648.x. Epub 2008 Sep 16. J Neurochem. 2008. PMID: 18761713 Free PMC article.

5

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand.

Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. J Neurosci. 2008 Oct 15;28(42):10696-710. doi: 10.1523/JNEUROSCI.1207-08.2008. J Neurosci. 2008. PMID: 18923045 Free PMC article.

6

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression.

Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Martel MA, et al. Among authors: hardingham ge. Channels (Austin). 2009 Jan-Feb;3(1):12-5. doi: 10.4161/chan.3.1.7864. Epub 2009 Jan 16. Channels (Austin). 2009. PMID: 19221512 Free article.

7

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin.

Soriano FX, Baxter P, Murray LM, Sporn MB, Gillingwater TH, Hardingham GE. Soriano FX, et al. Among authors: hardingham ge. Mol Cells. 2009 Mar 31;27(3):279-82. doi: 10.1007/s10059-009-0050-y. Epub 2009 Mar 19. Mol Cells. 2009. PMID: 19326073 Free PMC article. Review.

8

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S. Patani R, et al. Among authors: hardingham ge. PLoS One. 2009 Oct 6;4(10):e7327. doi: 10.1371/journal.pone.0007327. PLoS One. 2009. PMID: 19806200 Free PMC article.

9

Suppression of the intrinsic apoptosis pathway by synaptic activity.

Léveillé F, Papadia S, Fricker M, Bell KF, Soriano FX, Martel MA, Puddifoot C, Habel M, Wyllie DJ, Ikonomidou C, Tolkovsky AM, Hardingham GE. Léveillé F, et al. Among authors: hardingham ge. J Neurosci. 2010 Feb 17;30(7):2623-35. doi: 10.1523/JNEUROSCI.5115-09.2010. J Neurosci. 2010. PMID: 20164347 Free PMC article.

10

To die or not to die? Current questions in cell death signalling.

Leaver HA, Hardingham G. Leaver HA, et al. Mol Neurobiol. 2010 Aug;42(1):1-3. doi: 10.1007/s12035-010-8140-6. Mol Neurobiol. 2010. PMID: 20480261 No abstract available.

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