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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS. Weinberg F, et al. Among authors: mutlu gm. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421486 Free PMC article.
Incidence and outcomes of acute lung injury.
Mutlu GM, Budinger GR. Mutlu GM, et al. N Engl J Med. 2006 Jan 26;354(4):416-7; author reply 416-7. doi: 10.1056/NEJMc053159. N Engl J Med. 2006. PMID: 16436776 No abstract available.
Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS. Budinger GR, et al. Among authors: mutlu gm. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4604-9. doi: 10.1073/pnas.0507604103. Epub 2006 Mar 14. Proc Natl Acad Sci U S A. 2006. PMID: 16537427 Free PMC article.
Air pollution impairs lung's ability to clear edema fluid.
Mutlu GM, Bellmeyer A, Budinger GR. Mutlu GM, et al. Am J Cardiol. 2006 Aug 1;98(3):423-4. doi: 10.1016/j.amjcard.2006.02.026. Epub 2006 Apr 19. Am J Cardiol. 2006. PMID: 16860038 No abstract available.
Leptin resistance protects mice from hyperoxia-induced acute lung injury.
Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM. Bellmeyer A, et al. Among authors: mutlu gm. Am J Respir Crit Care Med. 2007 Mar 15;175(6):587-94. doi: 10.1164/rccm.200603-312OC. Epub 2006 Dec 21. Am J Respir Crit Care Med. 2007. PMID: 17185651 Free PMC article.
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR. Mutlu GM, et al. J Clin Invest. 2007 Oct;117(10):2952-61. doi: 10.1172/JCI30639. J Clin Invest. 2007. PMID: 17885684 Free PMC article.
Stretch-induced activation of AMP kinase in the lung requires dystroglycan.
Budinger GR, Urich D, DeBiase PJ, Chiarella SE, Burgess ZO, Baker CM, Soberanes S, Mutlu GM, Jones JC. Budinger GR, et al. Among authors: mutlu gm. Am J Respir Cell Mol Biol. 2008 Dec;39(6):666-72. doi: 10.1165/rcmb.2007-0432OC. Epub 2008 Jun 12. Am J Respir Cell Mol Biol. 2008. PMID: 18556591 Free PMC article.
Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.
Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Soberanes S, et al. Among authors: mutlu gm. J Biol Chem. 2009 Jan 23;284(4):2176-86. doi: 10.1074/jbc.M808844200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033436 Free PMC article.
170 results