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Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ.
Kim DH, Vanella L, Inoue K, Burgess A, Gotlinger K, Manthati VL, Koduru SR, Zeldin DC, Falck JR, Schwartzman ML, Abraham NG. Kim DH, et al. Among authors: abraham ng. Stem Cells Dev. 2010 Dec;19(12):1863-73. doi: 10.1089/scd.2010.0098. Epub 2010 Oct 9. Stem Cells Dev. 2010. PMID: 20412023 Free PMC article.
Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes.
Vanella L, Kim DH, Sodhi K, Barbagallo I, Burgess AP, Falck JR, Schwartzman ML, Abraham NG. Vanella L, et al. Among authors: abraham ng. Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):54-62. doi: 10.1016/j.prostaglandins.2011.07.005. Epub 2011 Jul 27. Prostaglandins Other Lipid Mediat. 2011. PMID: 21821145 Free PMC article.
11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells.
Sacerdoti D, Colombrita C, Di Pascoli M, Schwartzman ML, Bolognesi M, Falck JR, Gatta A, Abraham NG. Sacerdoti D, et al. Among authors: abraham ng. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):155-61. doi: 10.1016/j.prostaglandins.2006.07.001. Epub 2006 Aug 30. Prostaglandins Other Lipid Mediat. 2007. PMID: 17164143
Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells.
Kim DH, Burgess AP, Li M, Tsenovoy PL, Addabbo F, McClung JA, Puri N, Abraham NG. Kim DH, et al. Among authors: abraham ng. J Pharmacol Exp Ther. 2008 Jun;325(3):833-40. doi: 10.1124/jpet.107.135285. Epub 2008 Mar 11. J Pharmacol Exp Ther. 2008. PMID: 18334666
390 results