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Page 1
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M. Coomaraswamy J, et al. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7969-74. doi: 10.1073/pnas.1001056107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385796 Free PMC article.
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology.
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, Jucker M. Radde R, et al. Among authors: coomaraswamy j. EMBO Rep. 2006 Sep;7(9):940-6. doi: 10.1038/sj.embor.7400784. Epub 2006 Aug 11. EMBO Rep. 2006. PMID: 16906128 Free PMC article.
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M. Meyer-Luehmann M, et al. Among authors: coomaraswamy j. Science. 2006 Sep 22;313(5794):1781-4. doi: 10.1126/science.1131864. Science. 2006. PMID: 16990547
Cystatin C modulates cerebral beta-amyloidosis.
Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica ML, Winkler DT, Staufenbiel M, Levy E, Grubb A, Jucker M. Kaeser SA, et al. Among authors: coomaraswamy j. Nat Genet. 2007 Dec;39(12):1437-9. doi: 10.1038/ng.2007.23. Epub 2007 Nov 18. Nat Genet. 2007. PMID: 18026102
Modeling familial British dementia in transgenic mice.
Pickford F, Coomaraswamy J, Jucker M, McGowan E. Pickford F, et al. Among authors: coomaraswamy j. Brain Pathol. 2006 Jan;16(1):80-5. doi: 10.1111/j.1750-3639.2006.tb00564.x. Brain Pathol. 2006. PMID: 16612985 Free PMC article. Review.
Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
Mastrangelo P, Mathews PM, Chishti MA, Schmidt SD, Gu Y, Yang J, Mazzella MJ, Coomaraswamy J, Horne P, Strome B, Pelly H, Levesque G, Ebeling C, Jiang Y, Nixon RA, Rozmahel R, Fraser PE, St George-Hyslop P, Carlson GA, Westaway D. Mastrangelo P, et al. Among authors: coomaraswamy j. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8972-7. doi: 10.1073/pnas.0500940102. Epub 2005 Jun 10. Proc Natl Acad Sci U S A. 2005. PMID: 15951428 Free PMC article.
In vivo reduction of amyloid-beta by a mutant copper transporter.
Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D. Phinney AL, et al. Among authors: coomaraswamy j. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14193-8. doi: 10.1073/pnas.2332851100. Epub 2003 Nov 14. Proc Natl Acad Sci U S A. 2003. PMID: 14617772 Free PMC article.
20 results