McMahon M - Search Results

1

Resiliency and vulnerability in the HER2-HER3 tumorigenic driver.

Amin DN, Sergina N, Ahuja D, McMahon M, Blair JA, Wang D, Hann B, Koch KM, Shokat KM, Moasser MM. Amin DN, et al. Among authors: mcmahon m. Sci Transl Med. 2010 Jan 27;2(16):16ra7. doi: 10.1126/scitranslmed.3000389. Sci Transl Med. 2010. PMID: 20371474 Free PMC article.

2

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

Collisson EA, Trejo CL, Silva JM, Gu S, Korkola JE, Heiser LM, Charles RP, Rabinovich BA, Hann B, Dankort D, Spellman PT, Phillips WA, Gray JW, McMahon M. Collisson EA, et al. Among authors: mcmahon m. Cancer Discov. 2012 Aug;2(8):685-93. doi: 10.1158/2159-8290.CD-11-0347. Epub 2012 May 24. Cancer Discov. 2012. PMID: 22628411 Free PMC article.

3

BRAFV600E cooperates with PI3K signaling, independent of AKT, to regulate melanoma cell proliferation.

Silva JM, Bulman C, McMahon M. Silva JM, et al. Among authors: mcmahon m. Mol Cancer Res. 2014 Mar;12(3):447-63. doi: 10.1158/1541-7786.MCR-13-0224-T. Epub 2014 Jan 14. Mol Cancer Res. 2014. PMID: 24425783 Free PMC article.

4

Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events.

Hambleton J, McMahon M, DeFranco AL. Hambleton J, et al. Among authors: mcmahon m. J Exp Med. 1995 Jul 1;182(1):147-54. doi: 10.1084/jem.182.1.147. J Exp Med. 1995. PMID: 7790814 Free PMC article.

5

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK.

Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. Minden A, et al. Among authors: mcmahon m. Science. 1994 Dec 9;266(5191):1719-23. doi: 10.1126/science.7992057. Science. 1994. PMID: 7992057

6

Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB.

Mirza AM, Kohn AD, Roth RA, McMahon M. Mirza AM, et al. Among authors: mcmahon m. Cell Growth Differ. 2000 Jun;11(6):279-92. Cell Growth Differ. 2000. PMID: 10910095

7

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasazuki T, McMahon M, Oren M, McCormick F. Ries S, et al. Among authors: mcmahon m. Cell. 2000 Oct 13;103(2):321-30. doi: 10.1016/s0092-8674(00)00123-9. Cell. 2000. PMID: 11057904 Free article.

8

Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.

Hansen SH, Zegers MM, Woodrow M, Rodriguez-Viciana P, Chardin P, Mostov KE, McMahon M. Hansen SH, et al. Among authors: mcmahon m. Mol Cell Biol. 2000 Dec;20(24):9364-75. doi: 10.1128/MCB.20.24.9364-9375.2000. Mol Cell Biol. 2000. PMID: 11094087 Free PMC article.

9

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.

Woods D, Cherwinski H, Venetsanakos E, Bhat A, Gysin S, Humbert M, Bray PF, Saylor VL, McMahon M. Woods D, et al. Among authors: mcmahon m. Mol Cell Biol. 2001 May;21(9):3192-205. doi: 10.1128/MCB.21.9.3192-3205.2001. Mol Cell Biol. 2001. PMID: 11287623 Free PMC article.

10

Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.

Anders M, Christian C, McMahon M, McCormick F, Korn WM. Anders M, et al. Among authors: mcmahon m. Cancer Res. 2003 May 1;63(9):2088-95. Cancer Res. 2003. PMID: 12727824

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