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SARS-COV-2 induced Diarrhea is inflammatory, Ca 2+ Dependent and involves activation of calcium activated Cl channels.
Donowitz M, Tse CM, Dokladny K, Rawat M, Horwitz I, Ye C, Kell A, Lin R, Lee S, Guo C, Tsai SJ, Cox A, Gould S, In J, Bradfute S, Zachos NC, Kovbasnjuk O. Donowitz M, et al. Among authors: zachos nc. bioRxiv [Preprint]. 2021 Apr 28:2021.04.27.441695. doi: 10.1101/2021.04.27.441695. bioRxiv. 2021. PMID: 33948596 Free PMC article. Preprint.
NHERF family and NHE3 regulation.
Donowitz M, Cha B, Zachos NC, Brett CL, Sharma A, Tse CM, Li X. Donowitz M, et al. Among authors: zachos nc. J Physiol. 2005 Aug 15;567(Pt 1):3-11. doi: 10.1113/jphysiol.2005.090399. Epub 2005 May 19. J Physiol. 2005. PMID: 15905209 Free PMC article. Review.
Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea.
Sullivan S, Alex P, Dassopoulos T, Zachos NC, Iacobuzio-Donahue C, Donowitz M, Brant SR, Cuffari C, Harris ML, Datta LW, Conklin L, Chen Y, Li X. Sullivan S, et al. Among authors: zachos nc. Inflamm Bowel Dis. 2009 Feb;15(2):261-74. doi: 10.1002/ibd.20743. Inflamm Bowel Dis. 2009. PMID: 18942765 Free PMC article.
Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.
Donowitz M, Singh S, Singh P, Chakraborty M, Chen Y, Murtazina R, Gucek M, Cole RN, Zachos NC, Salahuddin FF, Kovbasnjuk O, Broere N, Smalley-Freed WG, Reynolds AB, Hubbard AL, Seidler U, Weinman E, de Jonge HR, Hogema BM, Li X. Donowitz M, et al. Among authors: zachos nc. Physiol Genomics. 2011 Jun 15;43(11):674-84. doi: 10.1152/physiolgenomics.00258.2010. Epub 2011 Mar 22. Physiol Genomics. 2011. PMID: 21427361 Free PMC article.
88 results