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Page 1
Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics.
Beres SB, Carroll RK, Shea PR, Sitkiewicz I, Martinez-Gutierrez JC, Low DE, McGeer A, Willey BM, Green K, Tyrrell GJ, Goldman TD, Feldgarden M, Birren BW, Fofanov Y, Boos J, Wheaton WD, Honisch C, Musser JM. Beres SB, et al. Among authors: shea pr. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4371-6. doi: 10.1073/pnas.0911295107. Epub 2010 Feb 8. Proc Natl Acad Sci U S A. 2010. PMID: 20142485 Free PMC article.
Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations.
Shea PR, Beres SB, Flores AR, Ewbank AL, Gonzalez-Lugo JH, Martagon-Rosado AJ, Martinez-Gutierrez JC, Rehman HA, Serrano-Gonzalez M, Fittipaldi N, Ayers SD, Webb P, Willey BM, Low DE, Musser JM. Shea PR, et al. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5039-44. doi: 10.1073/pnas.1016282108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383167 Free PMC article.
Group A Streptococcus emm gene types in pharyngeal isolates, Ontario, Canada, 2002-2010.
Shea PR, Ewbank AL, Gonzalez-Lugo JH, Martagon-Rosado AJ, Martinez-Gutierrez JC, Rehman HA, Serrano-Gonzalez M, Fittipaldi N, Beres SB, Flores AR, Low DE, Willey BM, Musser JM. Shea PR, et al. Emerg Infect Dis. 2011 Nov;17(11):2010-7. doi: 10.3201/eid1711.110159. Emerg Infect Dis. 2011. PMID: 22099088 Free PMC article.
Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus.
Shea PR, Virtaneva K, Kupko JJ 3rd, Porcella SF, Barry WT, Wright FA, Kobayashi SD, Carmody A, Ireland RM, Sturdevant DE, Ricklefs SM, Babar I, Johnson CA, Graham MR, Gardner DJ, Bailey JR, Parnell MJ, Deleo FR, Musser JM. Shea PR, et al. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4693-8. doi: 10.1073/pnas.0906384107. Epub 2010 Feb 23. Proc Natl Acad Sci U S A. 2010. PMID: 20179180 Free PMC article.
Polymorphisms in regulator of protease B (RopB) alter disease phenotype and strain virulence of serotype M3 group A Streptococcus.
Olsen RJ, Laucirica DR, Watkins ME, Feske ML, Garcia-Bustillos JR, Vu C, Cantu C, Shelburne SA 3rd, Fittipaldi N, Kumaraswami M, Shea PR, Flores AR, Beres SB, Lovgren M, Tyrrell GJ, Efstratiou A, Low DE, Van Beneden CA, Musser JM. Olsen RJ, et al. Among authors: shea pr. J Infect Dis. 2012 Jun;205(11):1719-29. doi: 10.1093/infdis/jir825. Epub 2012 Jan 18. J Infect Dis. 2012. PMID: 22262791 Free PMC article.
Full-genome dissection of an epidemic of severe invasive disease caused by a hypervirulent, recently emerged clone of group A Streptococcus.
Fittipaldi N, Beres SB, Olsen RJ, Kapur V, Shea PR, Watkins ME, Cantu CC, Laucirica DR, Jenkins L, Flores AR, Lovgren M, Ardanuy C, Liñares J, Low DE, Tyrrell GJ, Musser JM. Fittipaldi N, et al. Among authors: shea pr. Am J Pathol. 2012 Apr;180(4):1522-34. doi: 10.1016/j.ajpath.2011.12.037. Epub 2012 Feb 11. Am J Pathol. 2012. PMID: 22330677
Lower respiratory tract infection in cynomolgus macaques (Macaca fascicularis) infected with group A Streptococcus.
Olsen RJ, Ashraf M, Gonulal VE, Ayeras AA, Cantu C, Shea PR, Carroll RK, Humbird T, Greaver JL, Swain JL, Chang E, Ragasa W, Jenkins L, Lally KP, Blasdel T, Cagle P, Musser JM. Olsen RJ, et al. Among authors: shea pr. Microb Pathog. 2010 Dec;49(6):336-47. doi: 10.1016/j.micpath.2010.06.012. Epub 2010 Jul 30. Microb Pathog. 2010. PMID: 20674736
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.
McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, Buchbinder S, Carrington MN, Cossarizza A, Dalmau J, De Luca A, Goedert JJ, Gurdasani D, Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, Poli G, Sandhu MS, Schuitemaker H, Shea PR, Theodorou I, Walker BD, Weintrob AC, Winkler CA, Wolinsky SM, Raychaudhuri S, Goldstein DB, Telenti A, de Bakker PI, Zagury JF, Fellay J. McLaren PJ, et al. Among authors: shea pr. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14658-63. doi: 10.1073/pnas.1514867112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26553974 Free PMC article.
Evaluating the Impact of Functional Genetic Variation on HIV-1 Control.
McLaren PJ, Pulit SL, Gurdasani D, Bartha I, Shea PR, Pomilla C, Gupta N, Gkrania-Klotsas E, Young EH, Bannert N, Del Amo J, Gill MJ, Gilmour J, Kellam P, Kelleher AD, Sönnerborg A, Zangerle R, Post FA, Fisher M, Haas DW, Walker BD, Porter K, Goldstein DB, Sandhu MS, de Bakker PIW, Fellay J. McLaren PJ, et al. Among authors: shea pr. J Infect Dis. 2017 Nov 27;216(9):1063-1069. doi: 10.1093/infdis/jix470. J Infect Dis. 2017. PMID: 28968755 Free PMC article.
37 results