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Complete Combinatorial Mutational Enumeration of a protein functional site enables sequence-landscape mapping and identifies highly-mutated variants that retain activity.
Colom MS, Vucinic J, Adolf-Bryfogle J, Bowman JW, Verel S, Moczygemba I, Schiex T, Simoncini D, Bahl CD. Colom MS, et al. Among authors: bahl cd. Res Sq [Preprint]. 2023 Sep 11:rs.3.rs-2248327. doi: 10.21203/rs.3.rs-2248327/v2. Res Sq. 2023. Update in: Protein Sci. 2024 Aug;33(8):e5109. doi: 10.1002/pro.5109. PMID: 36482980 Free PMC article. Updated. Preprint.
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