Hedges LK - Search Results

1

Transcripts from a novel BMPR2 termination mutation escape nonsense mediated decay by downstream translation re-initiation: implications for treating pulmonary hypertension.

Hamid R, Hedges LK, Austin E, Phillips JA 3rd, Loyd JE, Cogan JD. Hamid R, et al. Among authors: hedges lk. Clin Genet. 2010 Mar;77(3):280-6. doi: 10.1111/j.1399-0004.2009.01311.x. Epub 2010 Jan 20. Clin Genet. 2010. PMID: 20095988 Free PMC article.

2

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

Flynn C, Zheng S, Yan L, Hedges L, Womack B, Fessel J, Cogan J, Austin E, Loyd J, West J, Zhao Z, Hamid R. Flynn C, et al. Am J Respir Cell Mol Biol. 2012 Jul;47(1):20-7. doi: 10.1165/rcmb.2011-0251OC. Epub 2012 Feb 3. Am J Respir Cell Mol Biol. 2012. PMID: 22312021 Free PMC article.

3

Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.

Cogan J, Austin E, Hedges L, Womack B, West J, Loyd J, Hamid R. Cogan J, et al. Circulation. 2012 Oct 9;126(15):1907-16. doi: 10.1161/CIRCULATIONAHA.112.106245. Epub 2012 Aug 24. Circulation. 2012. PMID: 22923426 Free PMC article.

4

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females.

Austin ED, Cogan JD, West JD, Hedges LK, Hamid R, Dawson EP, Wheeler LA, Parl FF, Loyd JE, Phillips JA 3rd. Austin ED, et al. Among authors: hedges lk. Eur Respir J. 2009 Nov;34(5):1093-9. doi: 10.1183/09031936.00010409. Epub 2009 Apr 8. Eur Respir J. 2009. PMID: 19357154 Free PMC article.

5

Gross BMPR2 gene rearrangements constitute a new cause for primary pulmonary hypertension.

Cogan JD, Vnencak-Jones CL, Phillips JA 3rd, Lane KB, Wheeler LA, Robbins IM, Garrison G, Hedges LK, Loyd JE. Cogan JD, et al. Among authors: hedges lk. Genet Med. 2005 Mar;7(3):169-74. doi: 10.1097/01.gim.0000156525.09595.e9. Genet Med. 2005. PMID: 15775752

6

High frequency of BMPR2 exonic deletions/duplications in familial pulmonary arterial hypertension.

Cogan JD, Pauciulo MW, Batchman AP, Prince MA, Robbins IM, Hedges LK, Stanton KC, Wheeler LA, Phillips JA 3rd, Loyd JE, Nichols WC. Cogan JD, et al. Among authors: hedges lk. Am J Respir Crit Care Med. 2006 Sep 1;174(5):590-8. doi: 10.1164/rccm.200602-165OC. Epub 2006 May 25. Am J Respir Crit Care Med. 2006. PMID: 16728714 Free PMC article.

7

Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele.

Hamid R, Cogan JD, Hedges LK, Austin E, Phillips JA 3rd, Newman JH, Loyd JE. Hamid R, et al. Among authors: hedges lk. Hum Mutat. 2009 Apr;30(4):649-54. doi: 10.1002/humu.20922. Hum Mutat. 2009. PMID: 19206171 Free PMC article.

8

Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism.

Chen X, Talati M, Fessel JP, Hemnes AR, Gladson S, French J, Shay S, Trammell A, Phillips JA, Hamid R, Cogan JD, Dawson EP, Womble KE, Hedges LK, Martinez EG, Wheeler LA, Loyd JE, Majka SJ, West J, Austin ED. Chen X, et al. Among authors: hedges lk. Circulation. 2016 Jan 5;133(1):82-97. doi: 10.1161/CIRCULATIONAHA.115.016133. Epub 2015 Oct 20. Circulation. 2016. PMID: 26487756 Free PMC article.

9

Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression.

Austin ED, Menon S, Hemnes AR, Robinson LR, Talati M, Fox KL, Cogan JD, Hamid R, Hedges LK, Robbins I, Lane K, Newman JH, Loyd JE, West J. Austin ED, et al. Among authors: hedges lk. Pulm Circ. 2011 Jul-Sep;1(3):389-98. doi: 10.4103/2045-8932.87308. Pulm Circ. 2011. PMID: 22140629 Free PMC article.

10

The Y Chromosome Regulates BMPR2 Expression via SRY: A Possible Reason "Why" Fewer Males Develop Pulmonary Arterial Hypertension.

Yan L, Cogan JD, Hedges LK, Nunley B, Hamid R, Austin ED. Yan L, et al. Among authors: hedges lk. Am J Respir Crit Care Med. 2018 Dec 15;198(12):1581-1583. doi: 10.1164/rccm.201802-0308LE. Am J Respir Crit Care Med. 2018. PMID: 30252494 Free PMC article. No abstract available.

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