Chu S - Search Results

1

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells.

Heaney NB, Pellicano F, Zhang B, Crawford L, Chu S, Kazmi SM, Allan EK, Jorgensen HG, Irvine AE, Bhatia R, Holyoake TL. Heaney NB, et al. Among authors: chu s. Blood. 2010 Mar 18;115(11):2241-50. doi: 10.1182/blood-2008-06-164582. Epub 2010 Jan 12. Blood. 2010. PMID: 20068223 Free PMC article.

2

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells.

Zhang B, Chu S, Agarwal P, Campbell VL, Hopcroft L, Jørgensen HG, Lin A, Gaal K, Holyoake TL, Bhatia R. Zhang B, et al. Among authors: chu s. Blood. 2016 Dec 8;128(23):2671-2682. doi: 10.1182/blood-2015-11-679928. Epub 2016 Sep 12. Blood. 2016. PMID: 27621307 Free PMC article.

3

BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells.

Chu S, Holtz M, Gupta M, Bhatia R. Chu S, et al. Blood. 2004 Apr 15;103(8):3167-74. doi: 10.1182/blood-2003-04-1271. Epub 2003 Dec 11. Blood. 2004. PMID: 15070699 Free article.

4

Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment.

Chu S, Xu H, Shah NP, Snyder DS, Forman SJ, Sawyers CL, Bhatia R. Chu S, et al. Blood. 2005 Mar 1;105(5):2093-8. doi: 10.1182/blood-2004-03-1114. Epub 2004 Sep 2. Blood. 2005. PMID: 15345592 Free article.

5

The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia.

Oehler VG, Gooley T, Snyder DS, Johnston L, Lin A, Cummings CC, Chu S, Bhatia R, Forman SJ, Negrin RS, Appelbaum FR, Radich JP. Oehler VG, et al. Among authors: chu s. Blood. 2007 Feb 15;109(4):1782-9. doi: 10.1182/blood-2006-06-031682. Epub 2006 Oct 24. Blood. 2007. PMID: 17062727 Free PMC article.

6

Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells.

Modi H, McDonald T, Chu S, Yee JK, Forman SJ, Bhatia R. Modi H, et al. Among authors: chu s. Blood. 2007 Jun 15;109(12):5411-21. doi: 10.1182/blood-2006-06-032490. Epub 2007 Mar 8. Blood. 2007. PMID: 17347407 Free PMC article.

7

Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.

Konig H, Copland M, Chu S, Jove R, Holyoake TL, Bhatia R. Konig H, et al. Among authors: chu s. Cancer Res. 2008 Dec 1;68(23):9624-33. doi: 10.1158/0008-5472.CAN-08-1131. Cancer Res. 2008. PMID: 19047139 Free PMC article.

8

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment.

Chu S, McDonald T, Lin A, Chakraborty S, Huang Q, Snyder DS, Bhatia R. Chu S, et al. Blood. 2011 Nov 17;118(20):5565-72. doi: 10.1182/blood-2010-12-327437. Epub 2011 Sep 19. Blood. 2011. PMID: 21931114 Free PMC article.

9

Role of BCR-ABL-Y177-mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors.

Chu S, McDonald T, Bhatia R. Chu S, et al. Leukemia. 2010 Apr;24(4):779-87. doi: 10.1038/leu.2010.24. Epub 2010 Mar 4. Leukemia. 2010. PMID: 20200561 Free PMC article.

10

BCR-tyrosine 177 plays an essential role in Ras and Akt activation and in human hematopoietic progenitor transformation in chronic myelogenous leukemia.

Chu S, Li L, Singh H, Bhatia R. Chu S, et al. Cancer Res. 2007 Jul 15;67(14):7045-53. doi: 10.1158/0008-5472.CAN-06-4312. Cancer Res. 2007. PMID: 17638918

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