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Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1.
J Immunol. 2010 Jan 1;184(1):476-87. doi: 10.4049/jimmunol.0902781. Epub 2009 Nov 30.
J Immunol. 2010.
PMID: 19949078
Free PMC article.
Responsiveness of HIV-specific CD4 T cells to PD-1 blockade.
Porichis F, Kwon DS, Zupkosky J, Tighe DP, McMullen A, Brockman MA, Pavlik DF, Rodriguez-Garcia M, Pereyra F, Freeman GJ, Kavanagh DG, Kaufmann DE.
Porichis F, et al. Among authors: tighe dp.
Blood. 2011 Jul 28;118(4):965-74. doi: 10.1182/blood-2010-12-328070. Epub 2011 Jun 7.
Blood. 2011.
PMID: 21652684
Free PMC article.
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IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.
Brockman MA, Kwon DS, Tighe DP, Pavlik DF, Rosato PC, Sela J, Porichis F, Le Gall S, Waring MT, Moss K, Jessen H, Pereyra F, Kavanagh DG, Walker BD, Kaufmann DE.
Brockman MA, et al. Among authors: tighe dp.
Blood. 2009 Jul 9;114(2):346-56. doi: 10.1182/blood-2008-12-191296. Epub 2009 Apr 13.
Blood. 2009.
PMID: 19365081
Free PMC article.
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CD4+ CD25+ regulatory T cells impair HIV-1-specific CD4 T cell responses by upregulating interleukin-10 production in monocytes.
Kwon DS, Angin M, Hongo T, Law KM, Johnson J, Porichis F, Hart MG, Pavlik DF, Tighe DP, Kavanagh DG, Streeck H, Addo MM, Kaufmann DE.
Kwon DS, et al. Among authors: tighe dp.
J Virol. 2012 Jun;86(12):6586-94. doi: 10.1128/JVI.06251-11. Epub 2012 Apr 11.
J Virol. 2012.
PMID: 22496237
Free PMC article.
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The balance between oligodendrocyte and astrocyte production in major white matter tracts is linearly related to serum total thyroxine.
Sharlin DS, Tighe D, Gilbert ME, Zoeller RT.
Sharlin DS, et al.
Endocrinology. 2008 May;149(5):2527-36. doi: 10.1210/en.2007-1431. Epub 2008 Feb 14.
Endocrinology. 2008.
PMID: 18276755
Free PMC article.
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Polybrominated diphenyl ether (DE-71) interferes with thyroid hormone action independent of effects on circulating levels of thyroid hormone in male rats.
Bansal R, Tighe D, Danai A, Rawn DF, Gaertner DW, Arnold DL, Gilbert ME, Zoeller RT.
Bansal R, et al.
Endocrinology. 2014 Oct;155(10):4104-12. doi: 10.1210/en.2014-1154. Epub 2014 Jul 25.
Endocrinology. 2014.
PMID: 25060363
Free PMC article.
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Maternal hypothyroidism decreases progesterone receptor expression in the cortical subplate of foetal rat brain.
Jahagirdar V, Zoeller TR, Tighe DP, Wagner CK.
Jahagirdar V, et al. Among authors: tighe dp.
J Neuroendocrinol. 2012 Aug;24(8):1126-34. doi: 10.1111/j.1365-2826.2012.02318.x.
J Neuroendocrinol. 2012.
PMID: 22435967
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