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A robust and highly efficient immune cell reprogramming system.
Bussmann LH, Schubert A, Vu Manh TP, De Andres L, Desbordes SC, Parra M, Zimmermann T, Rapino F, Rodriguez-Ubreva J, Ballestar E, Graf T. Bussmann LH, et al. Cell Stem Cell. 2009 Nov 6;5(5):554-66. doi: 10.1016/j.stem.2009.10.004. Cell Stem Cell. 2009. PMID: 19896445 Free article.
HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.
Barneda-Zahonero B, Román-González L, Collazo O, Rafati H, Islam AB, Bussmann LH, di Tullio A, De Andres L, Graf T, López-Bigas N, Mahmoudi T, Parra M. Barneda-Zahonero B, et al. Among authors: bussmann lh. PLoS Genet. 2013 May;9(5):e1003503. doi: 10.1371/journal.pgen.1003503. Epub 2013 May 16. PLoS Genet. 2013. PMID: 23696748 Free PMC article.