Southall N - Search Results

1

Dose-response modeling of high-throughput screening data.

Parham F, Austin C, Southall N, Huang R, Tice R, Portier C. Parham F, et al. Among authors: southall n. J Biomol Screen. 2009 Dec;14(10):1216-27. doi: 10.1177/1087057109349355. J Biomol Screen. 2009. PMID: 19828774 Free PMC article.

2

Compound cytotoxicity profiling using quantitative high-throughput screening.

Xia M, Huang R, Witt KL, Southall N, Fostel J, Cho MH, Jadhav A, Smith CS, Inglese J, Portier CJ, Tice RR, Austin CP. Xia M, et al. Among authors: southall n. Environ Health Perspect. 2008 Mar;116(3):284-91. doi: 10.1289/ehp.10727. Environ Health Perspect. 2008. PMID: 18335092 Free PMC article.

3

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening.

Huang R, Southall N, Cho MH, Xia M, Inglese J, Austin CP. Huang R, et al. Among authors: southall n. Chem Res Toxicol. 2008 Mar;21(3):659-67. doi: 10.1021/tx700365e. Epub 2008 Feb 19. Chem Res Toxicol. 2008. PMID: 18281954 Free PMC article.

4

Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features.

Huang R, Southall N, Xia M, Cho MH, Jadhav A, Nguyen DT, Inglese J, Tice RR, Austin CP. Huang R, et al. Among authors: southall n. Toxicol Sci. 2009 Dec;112(2):385-93. doi: 10.1093/toxsci/kfp231. Epub 2009 Oct 4. Toxicol Sci. 2009. PMID: 19805409 Free PMC article.

5

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.

Titus SA, Beacham D, Shahane SA, Southall N, Xia M, Huang R, Hooten E, Zhao Y, Shou L, Austin CP, Zheng W. Titus SA, et al. Among authors: southall n. Anal Biochem. 2009 Nov 1;394(1):30-8. doi: 10.1016/j.ab.2009.07.003. Epub 2009 Jul 5. Anal Biochem. 2009. PMID: 19583963 Free PMC article.

6

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

Johnson RL, Huang R, Jadhav A, Southall N, Wichterman J, MacArthur R, Xia M, Bi K, Printen J, Austin CP, Inglese J. Johnson RL, et al. Among authors: southall n. Mol Biosyst. 2009 Sep;5(9):1039-50. doi: 10.1039/b902021g. Epub 2009 Jun 19. Mol Biosyst. 2009. PMID: 19668870 Free PMC article.

7

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels.

Xia M, Shahane SA, Huang R, Titus SA, Shum E, Zhao Y, Southall N, Zheng W, Witt KL, Tice RR, Austin CP. Xia M, et al. Among authors: southall n. Toxicol Appl Pharmacol. 2011 May 1;252(3):250-8. doi: 10.1016/j.taap.2011.02.016. Epub 2011 Feb 26. Toxicol Appl Pharmacol. 2011. PMID: 21362439 Free PMC article.

8

Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing.

Sun H, Huang R, Xia M, Shahane S, Southall N, Wang Y. Sun H, et al. Among authors: southall n. Mol Inform. 2017 Apr;36(4):10.1002/minf.201600126. doi: 10.1002/minf.201600126. Epub 2016 Dec 21. Mol Inform. 2017. PMID: 28000393 Free PMC article.

9

Fluorescence spectroscopic profiling of compound libraries.

Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325

10

Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor.

Titus S, Neumann S, Zheng W, Southall N, Michael S, Klumpp C, Yasgar A, Shinn P, Thomas CJ, Inglese J, Gershengorn MC, Austin CP. Titus S, et al. Among authors: southall n. J Biomol Screen. 2008 Feb;13(2):120-7. doi: 10.1177/1087057107313786. Epub 2008 Jan 23. J Biomol Screen. 2008. PMID: 18216391 Free PMC article.

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