Lengyel E - Search Results

1

{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.

Kaur S, Kenny HA, Jagadeeswaran S, Zillhardt MR, Montag AG, Kistner E, Yamada SD, Mitra AK, Lengyel E. Kaur S, et al. Among authors: lengyel e. Am J Pathol. 2009 Nov;175(5):2184-96. doi: 10.2353/ajpath.2009.090028. Epub 2009 Oct 1. Am J Pathol. 2009. PMID: 19808644 Free PMC article.

2

Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy.

Mell LK, Kochanski JD, Roeske JC, Haslam JJ, Mehta N, Yamada SD, Hurteau JA, Collins YC, Lengyel E, Mundt AJ. Mell LK, et al. Among authors: lengyel e. Int J Radiat Oncol Biol Phys. 2006 Dec 1;66(5):1356-65. doi: 10.1016/j.ijrobp.2006.03.018. Epub 2006 Jun 6. Int J Radiat Oncol Biol Phys. 2006. PMID: 16757127

3

PDGFR-alpha as a potential therapeutic target in uterine sarcomas.

Adams SF, Hickson JA, Hutto JY, Montag AG, Lengyel E, Yamada SD. Adams SF, et al. Among authors: lengyel e. Gynecol Oncol. 2007 Mar;104(3):524-8. doi: 10.1016/j.ygyno.2006.09.013. Epub 2006 Oct 17. Gynecol Oncol. 2007. PMID: 17049587

4

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.

Sawada K, Radjabi AR, Shinomiya N, Kistner E, Kenny H, Becker AR, Turkyilmaz MA, Salgia R, Yamada SD, Vande Woude GF, Tretiakova MS, Lengyel E. Sawada K, et al. Among authors: lengyel e. Cancer Res. 2007 Feb 15;67(4):1670-9. doi: 10.1158/0008-5472.CAN-06-1147. Cancer Res. 2007. PMID: 17308108

5

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum.

Kenny HA, Krausz T, Yamada SD, Lengyel E. Kenny HA, et al. Among authors: lengyel e. Int J Cancer. 2007 Oct 1;121(7):1463-72. doi: 10.1002/ijc.22874. Int J Cancer. 2007. PMID: 17546601

6

Let-7 expression defines two differentiation stages of cancer.

Shell S, Park SM, Radjabi AR, Schickel R, Kistner EO, Jewell DA, Feig C, Lengyel E, Peter ME. Shell S, et al. Among authors: lengyel e. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11400-5. doi: 10.1073/pnas.0704372104. Epub 2007 Jun 28. Proc Natl Acad Sci U S A. 2007. PMID: 17600087 Free PMC article.

7

Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.

Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, Dinulescu DM, Lengyel E, Peter ME. Park SM, et al. Among authors: lengyel e. Cell Cycle. 2007 Nov 1;6(21):2585-90. doi: 10.4161/cc.6.21.4845. Epub 2007 Aug 6. Cell Cycle. 2007. PMID: 17957144

8

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.

Radjabi AR, Sawada K, Jagadeeswaran S, Eichbichler A, Kenny HA, Montag A, Bruno K, Lengyel E. Radjabi AR, et al. Among authors: lengyel e. J Biol Chem. 2008 Feb 1;283(5):2822-34. doi: 10.1074/jbc.M704855200. Epub 2007 Nov 29. J Biol Chem. 2008. PMID: 18048360 Free PMC article.

9

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

Kenny HA, Kaur S, Coussens LM, Lengyel E. Kenny HA, et al. Among authors: lengyel e. J Clin Invest. 2008 Apr;118(4):1367-79. doi: 10.1172/JCI33775. J Clin Invest. 2008. PMID: 18340378 Free PMC article.

10

Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.

Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E. Sawada K, et al. Among authors: lengyel e. Cancer Res. 2008 Apr 1;68(7):2329-39. doi: 10.1158/0008-5472.CAN-07-5167. Cancer Res. 2008. PMID: 18381440 Free PMC article.

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