Beasley JR - Search Results

1

Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model.

Ho KK, Beasley JR, Belanger L, Black D, Chan JH, Dunn D, Hu B, Klon A, Kultgen SG, Ohlmeyer M, Parlato SM, Ray PC, Pham Q, Rong Y, Roughton AL, Walker TL, Wright J, Xu K, Xu Y, Zhang L, Webb M. Ho KK, et al. Among authors: beasley jr. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6027-31. doi: 10.1016/j.bmcl.2009.09.046. Epub 2009 Sep 17. Bioorg Med Chem Lett. 2009. PMID: 19800787

2

Evaluation of compound interference in immobilized metal ion affinity-based fluorescence polarization detection with a four million member compound collection.

Beasley JR, Dunn DA, Walker TL, Parlato SM, Lehrach JM, Auld DS. Beasley JR, et al. Assay Drug Dev Technol. 2003 Jun;1(3):455-9. doi: 10.1089/154065803322163768. Assay Drug Dev Technol. 2003. PMID: 15090182

3

Miniaturized, ultra-high throughput screening of tyrosine kinases using homogeneous, competitive fluorescence immunoassays.

Beasley JR, McCoy PM, Walker TL, Dunn DA. Beasley JR, et al. Assay Drug Dev Technol. 2004 Apr;2(2):141-51. doi: 10.1089/154065804323056486. Assay Drug Dev Technol. 2004. PMID: 15165510

4

Kinase inhibitors as drugs for chronic inflammatory and immunological diseases: progress and challenges.

Rokosz LL, Beasley JR, Carroll CD, Lin T, Zhao J, Appell KC, Webb ML. Rokosz LL, et al. Among authors: beasley jr. Expert Opin Ther Targets. 2008 Jul;12(7):883-903. doi: 10.1517/14728222.12.7.883. Expert Opin Ther Targets. 2008. PMID: 18554156 Review.

5

Pathway-specific, species, and sub-type counterscreening for better GPCR hits in high throughput screening.

Swanson R, Beasley JR. Swanson R, et al. Among authors: beasley jr. Curr Pharm Biotechnol. 2010 Nov;11(7):757-63. doi: 10.2174/138920110792927775. Curr Pharm Biotechnol. 2010. PMID: 20809897 Review.

6

Protein thermal denaturation, side-chain models, and evolution: amino acid substitutions at a conserved helix-helix interface.

Pielak GJ, Auld DS, Beasley JR, Betz SF, Cohen DS, Doyle DF, Finger SA, Fredericks ZL, Hilgen-Willis S, Saunders AJ, et al. Pielak GJ, et al. Among authors: beasley jr. Biochemistry. 1995 Mar 14;34(10):3268-76. doi: 10.1021/bi00010a017. Biochemistry. 1995. PMID: 7880822

7

De novo amyloid proteins from designed combinatorial libraries.

West MW, Wang W, Patterson J, Mancias JD, Beasley JR, Hecht MH. West MW, et al. Among authors: beasley jr. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11211-6. doi: 10.1073/pnas.96.20.11211. Proc Natl Acad Sci U S A. 1999. PMID: 10500156 Free PMC article.

8

Searching for quantitative entropy-enthalpy compensation among protein variants.

Beasley JR, Doyle DF, Chen L, Cohen DS, Fine BR, Pielak GJ. Beasley JR, et al. Proteins. 2002 Nov 15;49(3):398-402. doi: 10.1002/prot.10189. Proteins. 2002. PMID: 12360529

9

Requirements for perpendicular helix pairing.

Beasley JR, Pielak GJ. Beasley JR, et al. Proteins. 1996 Sep;26(1):95-107. doi: 10.1002/(SICI)1097-0134(199609)26:1<95::AID-PROT9>3.0.CO;2-F. Proteins. 1996. PMID: 8880933

10

Partially formed native tertiary interactions in the A-state of cytochrome c.

Hostetter DR, Weatherly GT, Beasley JR, Bortone K, Cohen DS, Finger SA, Hardwidge P, Kakouras DS, Saunders AJ, Trojak SK, Waldner JC, Pielak GJ. Hostetter DR, et al. Among authors: beasley jr. J Mol Biol. 1999 Jun 11;289(3):639-44. doi: 10.1006/jmbi.1999.2764. J Mol Biol. 1999. PMID: 10356334

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