Chalmers MJ - Search Results

1

Unique ligand binding patterns between estrogen receptor alpha and beta revealed by hydrogen-deuterium exchange.

Dai SY, Burris TP, Dodge JA, Montrose-Rafizadeh C, Wang Y, Pascal BD, Chalmers MJ, Griffin PR. Dai SY, et al. Among authors: chalmers mj. Biochemistry. 2009 Oct 13;48(40):9668-76. doi: 10.1021/bi901149t. Biochemistry. 2009. PMID: 19739677 Free PMC article.

2

Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry.

Chalmers MJ, Busby SA, Pascal BD, He Y, Hendrickson CL, Marshall AG, Griffin PR. Chalmers MJ, et al. Anal Chem. 2006 Feb 15;78(4):1005-14. doi: 10.1021/ac051294f. Anal Chem. 2006. PMID: 16478090

3

A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, Southern MR, Griffin PR. Chalmers MJ, et al. J Biomol Tech. 2007 Sep;18(4):194-204. J Biomol Tech. 2007. PMID: 17916792 Free PMC article.

4

Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method.

Dai SY, Chalmers MJ, Bruning J, Bramlett KS, Osborne HE, Montrose-Rafizadeh C, Barr RJ, Wang Y, Wang M, Burris TP, Dodge JA, Griffin PR. Dai SY, et al. Among authors: chalmers mj. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7171-6. doi: 10.1073/pnas.0710802105. Epub 2008 May 12. Proc Natl Acad Sci U S A. 2008. PMID: 18474858 Free PMC article.

5

Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.

Zhang X, Chien EY, Chalmers MJ, Pascal BD, Gatchalian J, Stevens RC, Griffin PR. Zhang X, et al. Among authors: chalmers mj. Anal Chem. 2010 Feb 1;82(3):1100-8. doi: 10.1021/ac902484p. Anal Chem. 2010. PMID: 20058880 Free PMC article.

6

Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer.

Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Garcia-Ordonez RD, Pascal BD, Burris TP, Dodge JA, Griffin PR. Zhang J, et al. Among authors: chalmers mj. Structure. 2010 Oct 13;18(10):1332-41. doi: 10.1016/j.str.2010.07.007. Structure. 2010. PMID: 20947021 Free PMC article.

7

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, West GM, Griffin PR. Chalmers MJ, et al. Expert Rev Proteomics. 2011 Feb;8(1):43-59. doi: 10.1586/epr.10.109. Expert Rev Proteomics. 2011. PMID: 21329427 Free PMC article. Review.

8

Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data.

Chalmers MJ, Pascal BD, Willis S, Zhang J, Iturria SJ, Dodge JA, Griffin PR. Chalmers MJ, et al. Int J Mass Spectrom. 2011 Apr 30;302(1-3):59-68. doi: 10.1016/j.ijms.2010.08.002. Int J Mass Spectrom. 2011. PMID: 21528013 Free PMC article.

9

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR. West GM, et al. Among authors: chalmers mj. Structure. 2011 Oct 12;19(10):1424-32. doi: 10.1016/j.str.2011.08.001. Epub 2011 Sep 1. Structure. 2011. PMID: 21889352 Free PMC article.

10

Automated hydrogen/deuterium exchange electron transfer dissociation high resolution mass spectrometry measured at single-amide resolution.

Landgraf RR, Chalmers MJ, Griffin PR. Landgraf RR, et al. Among authors: chalmers mj. J Am Soc Mass Spectrom. 2012 Feb;23(2):301-9. doi: 10.1007/s13361-011-0298-2. Epub 2011 Dec 1. J Am Soc Mass Spectrom. 2012. PMID: 22131230 Free PMC article.

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