Thomson J - Search Results

1

Structure-based design of novel human Pin1 inhibitors (I).

Guo C, Hou X, Dong L, Dagostino E, Greasley S, Ferre R, Marakovits J, Johnson MC, Matthews D, Mroczkowski B, Parge H, Vanarsdale T, Popoff I, Piraino J, Margosiak S, Thomson J, Los G, Murray BW. Guo C, et al. Among authors: thomson j. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5613-6. doi: 10.1016/j.bmcl.2009.08.034. Epub 2009 Aug 13. Bioorg Med Chem Lett. 2009. PMID: 19729306

2

Structure-based design of novel human Pin1 inhibitors (II).

Dong L, Marakovits J, Hou X, Guo C, Greasley S, Dagostino E, Ferre R, Johnson MC, Kraynov E, Thomson J, Pathak V, Murray BW. Dong L, et al. Among authors: thomson j. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2210-4. doi: 10.1016/j.bmcl.2010.02.033. Epub 2010 Feb 14. Bioorg Med Chem Lett. 2010. PMID: 20207139

3

Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.

Kissinger CR, Rejto PA, Pelletier LA, Thomson JA, Showalter RE, Abreo MA, Agree CS, Margosiak S, Meng JJ, Aust RM, Vanderpool D, Li B, Tempczyk-Russell A, Villafranca JE. Kissinger CR, et al. Among authors: thomson ja. J Mol Biol. 2004 Sep 17;342(3):943-52. doi: 10.1016/j.jmb.2004.07.071. J Mol Biol. 2004. PMID: 15342248

4

Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme.

Love RA, Parge HE, Yu X, Hickey MJ, Diehl W, Gao J, Wriggers H, Ekker A, Wang L, Thomson JA, Dragovich PS, Fuhrman SA. Love RA, et al. Among authors: thomson ja. J Virol. 2003 Jul;77(13):7575-81. doi: 10.1128/jvi.77.13.7575-7581.2003. J Virol. 2003. PMID: 12805457 Free PMC article.

5

Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.

Solowiej J, Thomson JA, Ryan K, Luo C, He M, Lou J, Murray BW. Solowiej J, et al. Among authors: thomson ja. Biochemistry. 2008 Feb 26;47(8):2617-30. doi: 10.1021/bi702107v. Epub 2008 Feb 1. Biochemistry. 2008. PMID: 18237196

6

TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase.

Brin E, Wu K, Dagostino E, Meng-Chiang Kuo M, He Y, Shia WJ, Chen LC, Stempniak M, Hickey R, Almassy R, Showalter R, Thomson J. Brin E, et al. Among authors: thomson j. Oncotarget. 2018 Dec 11;9(97):36914-36928. doi: 10.18632/oncotarget.26398. eCollection 2018 Dec 11. Oncotarget. 2018. PMID: 30651925 Free PMC article.

7

Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis.

Heredia VV, Thomson J, Nettleton D, Sun S. Heredia VV, et al. Among authors: thomson j. Biochemistry. 2006 Jun 20;45(24):7553-62. doi: 10.1021/bi060253q. Biochemistry. 2006. PMID: 16768451

8

Glucose modulation of glucokinase activation by small molecules.

Ralph EC, Thomson J, Almaden J, Sun S. Ralph EC, et al. Among authors: thomson j. Biochemistry. 2008 Apr 29;47(17):5028-36. doi: 10.1021/bi702516y. Epub 2008 Mar 28. Biochemistry. 2008. PMID: 18370405

9

Improving Screening for Social Determinants of Health in an Outpatient Complex Care Clinic.

Randolph A, Butts B, White C, Auberger A, Bohache M, Goddard-Roaden C, Beck AF, Brinkman WB, Thomson J. Randolph A, et al. Among authors: thomson j. Pediatrics. 2024 Sep 24:e2023063086. doi: 10.1542/peds.2023-063086. Online ahead of print. Pediatrics. 2024. PMID: 39314185

10

A Strategy for the Formal C-N Cross-Coupling of Tertiary Amines.

Ledwith PR, Cooney ML, Bahou KA, García-Cárceles J, Thomson J, Bower J. Ledwith PR, et al. Among authors: thomson j. Angew Chem Int Ed Engl. 2024 Sep 2:e202411555. doi: 10.1002/anie.202411555. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39219402

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