Caprathe BW - Search Results

1

4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties.

Jaen JC, Wise LD, Caprathe BW, Tecle H, Bergmeier S, Humblet CC, Heffner TG, Meltzer LT, Pugsley TA. Jaen JC, et al. Among authors: caprathe bw. J Med Chem. 1990 Jan;33(1):311-7. doi: 10.1021/jm00163a051. J Med Chem. 1990. PMID: 1967314

2

Dopamine autoreceptor agonists as potential antipsychotics. 3.6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine.

Caprathe BW, Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT, Parvez M. Caprathe BW, et al. J Med Chem. 1991 Sep;34(9):2736-46. doi: 10.1021/jm00113a010. J Med Chem. 1991. PMID: 1680195

3

Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors.

Jaen JC, Caprathe BW, Pugsley TA, Wise LD, Akunne H. Jaen JC, et al. Among authors: caprathe bw. J Med Chem. 1993 Nov 26;36(24):3929-36. doi: 10.1021/jm00076a022. J Med Chem. 1993. PMID: 7902870

4

The discovery and structure-activity relationships of 1,2,3,6-tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine autoreceptor agonists and potential antipsychotic agents.

Wright JL, Caprathe BW, Downing DM, Glase SA, Heffner TG, Jaen JC, Johnson SJ, Kesten SR, MacKenzie RG, Meltzer LT, et al. Wright JL, et al. Among authors: caprathe bw. J Med Chem. 1994 Oct 14;37(21):3523-33. doi: 10.1021/jm00047a010. J Med Chem. 1994. PMID: 7932581

5

Pharmacological profile of the dopamine partial agonist, (+/-)-PD 128483 and its enantiomers.

Meltzer LT, Caprathe BW, Christoffersen CL, Corbin AE, Jaen JC, Ninteman FW, Pugsley TA, Serpa KA, Shih YH, Whetzel SZ, et al. Meltzer LT, et al. Among authors: caprathe bw. J Pharmacol Exp Ther. 1993 Sep;266(3):1177-89. J Pharmacol Exp Ther. 1993. PMID: 8103791

6

Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist.

Tecle H, Barrett SD, Lauffer DJ, Augelli-Szafran C, Brann MR, Callahan MJ, Caprathe BW, Davis RE, Doyle PD, Eubanks D, Lipiniski W, Mirzadegan T, Moos WH, Moreland DW, Nelson CB, Pavia MR, Raby C, Schwarz RD, Spencer CJ, Thomas AJ, Jaen JC. Tecle H, et al. Among authors: caprathe bw. J Med Chem. 1998 Jul 2;41(14):2524-36. doi: 10.1021/jm960683m. J Med Chem. 1998. PMID: 9651157

7

Synthesis of the enantiomers of reduced haloperidol.

Jaen JC, Caprathe BW, Priebe S, Wise LD. Jaen JC, et al. Among authors: caprathe bw. Pharm Res. 1991 Aug;8(8):1002-5. doi: 10.1023/a:1015800923078. Pharm Res. 1991. PMID: 1924152

8

Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor.

Jaen JC, Laborde E, Bucsh RA, Caprathe BW, Sorenson RJ, Fergus J, Spiegel K, Marks J, Dickerson MR, Davis RE. Jaen JC, et al. Among authors: caprathe bw. J Med Chem. 1995 Oct 27;38(22):4439-45. doi: 10.1021/jm00022a008. J Med Chem. 1995. PMID: 7473570

9

Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology.

Pool WF, Woolf TF, Reily MD, Caprathe BW, Emmerling MR, Jaen JC. Pool WF, et al. Among authors: caprathe bw. J Med Chem. 1996 Jul 19;39(15):3014-8. doi: 10.1021/jm9602266. J Med Chem. 1996. PMID: 8709135

10

2-amino-4H-3,1-benzoxazin-4-ones as inhibitors of C1r serine protease.

Hays SJ, Caprathe BW, Gilmore JL, Amin N, Emmerling MR, Michael W, Nadimpalli R, Nath R, Raser KJ, Stafford D, Watson D, Wang K, Jaen JC. Hays SJ, et al. Among authors: caprathe bw. J Med Chem. 1998 Mar 26;41(7):1060-7. doi: 10.1021/jm970394d. J Med Chem. 1998. PMID: 9544206

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