Jiang H - Search Results

1

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice.

Pan J, Liu T, Kim JY, Zhu D, Patel C, Cui ZH, Zhang X, Newgren JO, Reames A, Canivel D, Jesmok G, Pierce GF, Sommer JM, Jiang H. Pan J, et al. Among authors: jiang h. Blood. 2009 Sep 24;114(13):2802-11. doi: 10.1182/blood-2009-03-212423. Epub 2009 Aug 4. Blood. 2009. PMID: 19654409 Free article.

2

Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs.

Jiang H, Lillicrap D, Patarroyo-White S, Liu T, Qian X, Scallan CD, Powell S, Keller T, McMurray M, Labelle A, Nagy D, Vargas JA, Zhou S, Couto LB, Pierce GF. Jiang H, et al. Blood. 2006 Jul 1;108(1):107-15. doi: 10.1182/blood-2005-12-5115. Epub 2006 Mar 7. Blood. 2006. PMID: 16522813 Free article.

3

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment.

Mei B, Pan C, Jiang H, Tjandra H, Strauss J, Chen Y, Liu T, Zhang X, Severs J, Newgren J, Chen J, Gu JM, Subramanyam B, Fournel MA, Pierce GF, Murphy JE. Mei B, et al. Among authors: jiang h. Blood. 2010 Jul 15;116(2):270-9. doi: 10.1182/blood-2009-11-254755. Epub 2010 Mar 1. Blood. 2010. PMID: 20194895 Free article.

4

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients.

Powell JS, Josephson NC, Quon D, Ragni MV, Cheng G, Li E, Jiang H, Li L, Dumont JA, Goyal J, Zhang X, Sommer J, McCue J, Barbetti M, Luk A, Pierce GF. Powell JS, et al. Among authors: jiang h. Blood. 2012 Mar 29;119(13):3031-7. doi: 10.1182/blood-2011-09-382846. Epub 2012 Jan 5. Blood. 2012. PMID: 22223821 Free PMC article. Clinical Trial.

5

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice.

Seth Chhabra E, Liu T, Kulman J, Patarroyo-White S, Yang B, Lu Q, Drager D, Moore N, Liu J, Holthaus AM, Sommer JM, Ismail A, Rabinovich D, Liu Z, van der Flier A, Goodman A, Furcht C, Tie M, Carlage T, Mauldin R, Dobrowsky TM, Liu Z, Mercury O, Zhu L, Mei B, Schellenberger V, Jiang H, Pierce GF, Salas J, Peters R. Seth Chhabra E, et al. Among authors: jiang h. Blood. 2020 Apr 23;135(17):1484-1496. doi: 10.1182/blood.2019001292. Blood. 2020. PMID: 32078672 Free PMC article.

6

Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.

Scallan CD, Liu T, Parker AE, Patarroyo-White SL, Chen H, Jiang H, Vargas J, Nagy D, Powell SK, Wright JF, Sarkar R, Kazazian HH, McClelland A, Couto LB. Scallan CD, et al. Among authors: jiang h. Blood. 2003 Dec 1;102(12):3919-26. doi: 10.1182/blood-2003-01-0222. Epub 2003 Jul 31. Blood. 2003. PMID: 12893764 Free article.

7

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice.

Scallan CD, Jiang H, Liu T, Patarroyo-White S, Sommer JM, Zhou S, Couto LB, Pierce GF. Scallan CD, et al. Among authors: jiang h. Blood. 2006 Mar 1;107(5):1810-7. doi: 10.1182/blood-2005-08-3229. Epub 2005 Oct 25. Blood. 2006. PMID: 16249376 Free article.

8

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy.

Jiang H, Couto LB, Patarroyo-White S, Liu T, Nagy D, Vargas JA, Zhou S, Scallan CD, Sommer J, Vijay S, Mingozzi F, High KA, Pierce GF. Jiang H, et al. Blood. 2006 Nov 15;108(10):3321-8. doi: 10.1182/blood-2006-04-017913. Epub 2006 Jul 25. Blood. 2006. PMID: 16868252 Free PMC article.

9

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.

Shapiro AD, Ragni MV, Valentino LA, Key NS, Josephson NC, Powell JS, Cheng G, Thompson AR, Goyal J, Tubridy KL, Peters RT, Dumont JA, Euwart D, Li L, Hallén B, Gozzi P, Bitonti AJ, Jiang H, Luk A, Pierce GF. Shapiro AD, et al. Among authors: jiang h. Blood. 2012 Jan 19;119(3):666-72. doi: 10.1182/blood-2011-07-367003. Epub 2011 Nov 22. Blood. 2012. PMID: 22110246 Free PMC article. Clinical Trial.

10

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs.

Dumont JA, Liu T, Low SC, Zhang X, Kamphaus G, Sakorafas P, Fraley C, Drager D, Reidy T, McCue J, Franck HW, Merricks EP, Nichols TC, Bitonti AJ, Pierce GF, Jiang H. Dumont JA, et al. Among authors: jiang h. Blood. 2012 Mar 29;119(13):3024-30. doi: 10.1182/blood-2011-08-367813. Epub 2012 Jan 13. Blood. 2012. PMID: 22246033 Free PMC article.

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