Shibasaki T - Search Results

1

The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs.

Zhang CL, Katoh M, Shibasaki T, Minami K, Sunaga Y, Takahashi H, Yokoi N, Iwasaki M, Miki T, Seino S. Zhang CL, et al. Among authors: shibasaki t. Science. 2009 Jul 31;325(5940):607-10. doi: 10.1126/science.1172256. Science. 2009. PMID: 19644119

2

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

Shibasaki T, Sunaga Y, Fujimoto K, Kashima Y, Seino S. Shibasaki T, et al. J Biol Chem. 2004 Feb 27;279(9):7956-61. doi: 10.1074/jbc.M309068200. Epub 2003 Dec 3. J Biol Chem. 2004. PMID: 14660679 Free article.

3

Integration of ATP, cAMP, and Ca2+ signals in insulin granule exocytosis.

Shibasaki T, Sunaga Y, Seino S. Shibasaki T, et al. Diabetes. 2004 Dec;53 Suppl 3:S59-62. doi: 10.2337/diabetes.53.suppl_3.s59. Diabetes. 2004. PMID: 15561922

4

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino S. Shibasaki T, et al. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19333-8. doi: 10.1073/pnas.0707054104. Epub 2007 Nov 26. Proc Natl Acad Sci U S A. 2007. PMID: 18040047 Free PMC article.

5

Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function.

Niimura M, Miki T, Shibasaki T, Fujimoto W, Iwanaga T, Seino S. Niimura M, et al. Among authors: shibasaki t. J Cell Physiol. 2009 Jun;219(3):652-8. doi: 10.1002/jcp.21709. J Cell Physiol. 2009. PMID: 19170062

6

[Roles of the cAMP sensor Epac2A in insulin secretion].

Shibasaki T, Seino S. Shibasaki T, et al. Nihon Naika Gakkai Zasshi. 2011 May 10;100(5):1418-24. doi: 10.2169/naika.100.1418. Nihon Naika Gakkai Zasshi. 2011. PMID: 21702163 Review. Japanese. No abstract available.

7

Antidiabetic sulfonylureas and cAMP cooperatively activate Epac2A.

Takahashi T, Shibasaki T, Takahashi H, Sugawara K, Ono A, Inoue N, Furuya T, Seino S. Takahashi T, et al. Among authors: shibasaki t. Sci Signal. 2013 Oct 22;6(298):ra94. doi: 10.1126/scisignal.2004581. Sci Signal. 2013. PMID: 24150255

8

Structure and functional roles of Epac2 (Rapgef4).

Sugawara K, Shibasaki T, Takahashi H, Seino S. Sugawara K, et al. Among authors: shibasaki t. Gene. 2016 Jan 10;575(2 Pt 3):577-83. doi: 10.1016/j.gene.2015.09.029. Epub 2015 Sep 24. Gene. 2016. PMID: 26390815 Free PMC article. Review.

9

Cooperation between cAMP signalling and sulfonylurea in insulin secretion.

Shibasaki T, Takahashi T, Takahashi H, Seino S. Shibasaki T, et al. Diabetes Obes Metab. 2014 Sep;16 Suppl 1:118-25. doi: 10.1111/dom.12343. Diabetes Obes Metab. 2014. PMID: 25200305 Review.

10

Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.

Fujimoto K, Shibasaki T, Yokoi N, Kashima Y, Matsumoto M, Sasaki T, Tajima N, Iwanaga T, Seino S. Fujimoto K, et al. Among authors: shibasaki t. J Biol Chem. 2002 Dec 27;277(52):50497-502. doi: 10.1074/jbc.M210146200. Epub 2002 Oct 24. J Biol Chem. 2002. PMID: 12401793 Free article.

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