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VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function.
Markel TA, Wang Y, Herrmann JL, Crisostomo PR, Wang M, Novotny NM, Herring CM, Tan J, Lahm T, Meldrum DR. Markel TA, et al. Among authors: tan j. Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2308-14. doi: 10.1152/ajpheart.00565.2008. Epub 2008 Oct 10. Am J Physiol Heart Circ Physiol. 2008. PMID: 18849336 Free PMC article.
Estrogen receptor beta mediates increased activation of PI3K/Akt signaling and improved myocardial function in female hearts following acute ischemia.
Wang M, Wang Y, Weil B, Abarbanell A, Herrmann J, Tan J, Kelly M, Meldrum DR. Wang M, et al. Among authors: tan j. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R972-8. doi: 10.1152/ajpregu.00045.2009. Epub 2009 Feb 11. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19211725 Free PMC article.
Signal transducer and activator of transcription 3-stimulated hypoxia inducible factor-1alpha mediates estrogen receptor-alpha-induced mesenchymal stem cell vascular endothelial growth factor production.
Wang M, Tan J, Coffey A, Fehrenbacher J, Weil BR, Meldrum DR. Wang M, et al. Among authors: tan j. J Thorac Cardiovasc Surg. 2009 Jul;138(1):163-71, 171.e1. doi: 10.1016/j.jtcvs.2009.03.010. J Thorac Cardiovasc Surg. 2009. PMID: 19577074 Free PMC article.
Cell-based therapy for ischemic heart disease: a clinical update.
Herrmann JL, Abarbanell AM, Weil BR, Wang Y, Wang M, Tan J, Meldrum DR. Herrmann JL, et al. Among authors: tan j. Ann Thorac Surg. 2009 Nov;88(5):1714-22. doi: 10.1016/j.athoracsur.2009.05.079. Ann Thorac Surg. 2009. PMID: 19853156 Review.
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