Rohatagi S - Search Results

1

Population pharmacokinetic analyses to evaluate the influence of intrinsic and extrinsic factors on exposure of prasugrel active metabolite in TRITON-TIMI 38.

Wrishko RE, Ernest CS 2nd, Small DS, Li YG, Weerakkody GJ, Riesmeyer JR, Macias WL, Rohatagi S, Salazar DE, Antman EM, Wiviott SD, Braunwald E, Ni L. Wrishko RE, et al. Among authors: rohatagi s. J Clin Pharmacol. 2009 Aug;49(8):984-98. doi: 10.1177/0091270009337942. Epub 2009 Jun 22. J Clin Pharmacol. 2009. PMID: 19546250

2

Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.

Ernest CS 2nd, Small DS, Rohatagi S, Salazar DE, Wallentin L, Winters KJ, Wrishko RE. Ernest CS 2nd, et al. Among authors: rohatagi s. J Pharmacokinet Pharmacodyn. 2008 Dec;35(6):593-618. doi: 10.1007/s10928-008-9103-7. Epub 2008 Nov 21. J Pharmacokinet Pharmacodyn. 2008. PMID: 19023649 Clinical Trial.

3

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS 2nd, Rohatagi S, Farid NA, Jakubowski JA, Winters KJ. Li YG, et al. Among authors: rohatagi s. Platelets. 2009 Aug;20(5):316-27. doi: 10.1080/09537100903046317. Platelets. 2009. PMID: 19637095 Free article.

4

Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent.

Small DS, Li YG, Ernest CS 2nd, April JH, Farid NA, Payne CD, Winters KJ, Rohatagi S, Ni L. Small DS, et al. Among authors: rohatagi s. J Clin Pharmacol. 2011 Mar;51(3):321-32. doi: 10.1177/0091270010367429. Epub 2010 Apr 21. J Clin Pharmacol. 2011. PMID: 20410452 Clinical Trial.

5

Relationship between exposure to prasugrel active metabolite and clinical outcomes in the TRITON-TIMI 38 substudy.

Riesmeyer JS, Salazar DE, Weerakkody GJ, Ni L, Wrishko RE, Ernest CS 2nd, Luo J, Li YG, Small DS, Rohatagi S, Macias WL. Riesmeyer JS, et al. Among authors: rohatagi s. J Clin Pharmacol. 2012 Jun;52(6):789-97. doi: 10.1177/0091270011406280. Epub 2011 May 31. J Clin Pharmacol. 2012. PMID: 21628601 Clinical Trial.

6

Correlation of inhibition of platelet aggregation with cardiovascular and bleeding outcomes in acute coronary syndromes.

Wada R, Rohatagi S, Small D, Winters KJ, Salazar DE. Wada R, et al. Among authors: rohatagi s. J Clin Pharmacol. 2010 Aug;50(8):904-13. doi: 10.1177/0091270009353606. Epub 2010 Feb 10. J Clin Pharmacol. 2010. PMID: 20147617

7

Evaluation of population pharmacokinetics and exposure-response relationship with coadministration of amlodipine besylate and olmesartan medoxomil.

Rohatagi S, Carrothers TJ, Kshirsagar S, Khariton T, Lee J, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2008 Jul;48(7):823-36. doi: 10.1177/0091270008317847. Epub 2008 May 19. J Clin Pharmacol. 2008. PMID: 18490496 Clinical Trial.

8

Model-based development of a PPARgamma agonist, rivoglitazone, to aid dose selection and optimize clinical trial designs.

Rohatagi S, Carrothers TJ, Jin J, Jusko WJ, Khariton T, Walker J, Truitt K, Salazar DE. Rohatagi S, et al. J Clin Pharmacol. 2008 Dec;48(12):1420-9. doi: 10.1177/0091270008323260. Epub 2008 Oct 20. J Clin Pharmacol. 2008. PMID: 18936283 Clinical Trial.

9

Pharmacokinetics of amlodipine and olmesartan after administration of amlodipine besylate and olmesartan medoxomil in separate dosage forms and as a fixed-dose combination.

Rohatagi S, Lee J, Shenouda M, Haworth S, Bathala MS, Allison M, Rubets I, Heyrman R, Noveck R, Salazar DE. Rohatagi S, et al. J Clin Pharmacol. 2008 Nov;48(11):1309-22. doi: 10.1177/0091270008322176. J Clin Pharmacol. 2008. PMID: 18974285

10

Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor.

Rohatagi S, Kastrissios H, Gao Y, Zhang N, Xu J, Moberly J, Wada R, Yoshihara K, Takahashi M, Truitt K, Salazar D. Rohatagi S, et al. J Clin Pharmacol. 2007 Mar;47(3):358-70. doi: 10.1177/0091270006296152. J Clin Pharmacol. 2007. PMID: 17322148

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