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Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Yoon SS, et al. Among authors: jacks t. Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):1207-16. doi: 10.1016/j.ijrobp.2009.02.052. Int J Radiat Oncol Biol Phys. 2009. PMID: 19545786 Free PMC article.
Mouse models of human non-small-cell lung cancer: raising the bar.
Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T. Kim CF, et al. Among authors: jacks t. Cold Spring Harb Symp Quant Biol. 2005;70:241-50. doi: 10.1101/sqb.2005.70.037. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869760 Review.
Restoration of p53 function leads to tumour regression in vivo.
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T. Ventura A, et al. Among authors: jacks t. Nature. 2007 Feb 8;445(7128):661-5. doi: 10.1038/nature05541. Epub 2007 Jan 24. Nature. 2007. PMID: 17251932
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T. Kirsch DG, et al. Among authors: jacks t. Nat Med. 2007 Aug;13(8):992-7. doi: 10.1038/nm1602. Epub 2007 Aug 5. Nat Med. 2007. PMID: 17676052
Dicer1 functions as a haploinsufficient tumor suppressor.
Kumar MS, Pester RE, Chen CY, Lane K, Chin C, Lu J, Kirsch DG, Golub TR, Jacks T. Kumar MS, et al. Among authors: jacks t. Genes Dev. 2009 Dec 1;23(23):2700-4. doi: 10.1101/gad.1848209. Epub 2009 Nov 10. Genes Dev. 2009. PMID: 19903759 Free PMC article.
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.
Kirsch DG, Santiago PM, di Tomaso E, Sullivan JM, Hou WS, Dayton T, Jeffords LB, Sodha P, Mercer KL, Cohen R, Takeuchi O, Korsmeyer SJ, Bronson RT, Kim CF, Haigis KM, Jain RK, Jacks T. Kirsch DG, et al. Among authors: jacks t. Science. 2010 Jan 29;327(5965):593-6. doi: 10.1126/science.1166202. Epub 2009 Dec 17. Science. 2010. PMID: 20019247 Free PMC article.
Imaging primary lung cancers in mice to study radiation biology.
Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T. Kirsch DG, et al. Among authors: jacks t. Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):973-7. doi: 10.1016/j.ijrobp.2009.11.038. Int J Radiat Oncol Biol Phys. 2010. PMID: 20206017 Free PMC article.
438 results