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N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.
Melotte V, Lentjes MH, van den Bosch SM, Hellebrekers DM, de Hoon JP, Wouters KA, Daenen KL, Partouns-Hendriks IE, Stessels F, Louwagie J, Smits KM, Weijenberg MP, Sanduleanu S, Khalid-de Bakker CA, Oort FA, Meijer GA, Jonkers DM, Herman JG, de Bruïne AP, van Engeland M. Melotte V, et al. Among authors: van den bosch sm. J Natl Cancer Inst. 2009 Jul 1;101(13):916-27. doi: 10.1093/jnci/djp131. Epub 2009 Jun 17. J Natl Cancer Inst. 2009. PMID: 19535783
Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Derks S, Postma C, Moerkerk PT, van den Bosch SM, Carvalho B, Hermsen MA, Giaretti W, Herman JG, Weijenberg MP, de Bruïne AP, Meijer GA, van Engeland M. Derks S, et al. Among authors: van den bosch sm, van engeland m. Cell Oncol. 2006;28(5-6):247-57. doi: 10.1155/2006/846251. Cell Oncol. 2006. PMID: 17167178 Free PMC article.
Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Derks S, Postma C, Carvalho B, van den Bosch SM, Moerkerk PT, Herman JG, Weijenberg MP, de Bruïne AP, Meijer GA, van Engeland M. Derks S, et al. Among authors: van den bosch sm, van engeland m. Carcinogenesis. 2008 Feb;29(2):434-9. doi: 10.1093/carcin/bgm270. Epub 2007 Nov 28. Carcinogenesis. 2008. PMID: 18048385
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.
Hellebrekers DM, Lentjes MH, van den Bosch SM, Melotte V, Wouters KA, Daenen KL, Smits KM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker CA, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruïne AP, van Engeland M. Hellebrekers DM, et al. Among authors: van den bosch sm. Clin Cancer Res. 2009 Jun 15;15(12):3990-7. doi: 10.1158/1078-0432.CCR-09-0055. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509152
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
Derks S, Bosch LJ, Niessen HE, Moerkerk PT, van den Bosch SM, Carvalho B, Mongera S, Voncken JW, Meijer GA, de Bruïne AP, Herman JG, van Engeland M. Derks S, et al. Among authors: van den bosch sm. Carcinogenesis. 2009 Jun;30(6):1041-8. doi: 10.1093/carcin/bgp073. Epub 2009 Mar 27. Carcinogenesis. 2009. PMID: 19329758
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.
Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB. Schuebel KE, et al. PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31. PLoS Genet. 2007. PMID: 17892325 Free PMC article.
Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype.
Van der Auwera I, Van Laere SJ, Van den Bosch SM, Van den Eynden GG, Trinh BX, van Dam PA, Colpaert CG, van Engeland M, Van Marck EA, Vermeulen PB, Dirix LY. Van der Auwera I, et al. Among authors: van den bosch sm, van dam pa, van laere sj, van den eynden gg, van marck ea, van engeland m. Br J Cancer. 2008 Nov 18;99(10):1735-42. doi: 10.1038/sj.bjc.6604705. Epub 2008 Oct 7. Br J Cancer. 2008. PMID: 18841156 Free PMC article.
17 results